A tool for exploring the dynamics of innovative interventions for public health: the critical event card

Authors: Bernier J, Couturier Y, de Araújo Oliveira SR, de Sa RF, do Socorro Machado Freire M, Figueiró AC, Hartz Z, Medina MG, Potvin L, Samico I
Publication Year: 2017
Journal: International Journal of Public Health
Link: https://link.springer.com/article/10.1007%2Fs00038-016-0861-5

Public health interventions are increasingly represented as complex systems. Research tools for capturing the dynamic of interventions processes, however, are practically non-existent. This paper describes the development and proof of concept process of an analytical tool, the critical event card (CEC), which supports the representation and analysis of complex interventions’ evolution, based on critical events. […]
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Antileishmanial activity of meroditerpenoids from the macroalgae Cystoseira baccata

Authors: Barreira L, Bruno de Sousa C, Campino L, Conserva GA, Custódio L, Gangadhar KN, Lago JH, Laurenti MD, Levy D, Morais TR, Passero LF, Pereira H, Uemi M, Varela J, Vizetto-Duarte C
Publication Year: 2017
Journal: Experimental Parasitology
Link: https://www.sciencedirect.com/science/article/pii/S0014489417300371?via%3Dihub%20

The development of novel drugs for the treatment of leishmaniases continues to be crucial to overcome the severe impacts of these diseases on human and animal health. Several bioactivities have been described in extracts from macroalgae belonging to the Cystoseira genus. However, none of the studies has reported the chemical compounds responsible for the antileishmanial […]
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Implications of hepatitis C virus subtype 1a migration patterns for virus genetic sequencing policies in Italy

Authors: Aragri M, Balog D, Ceccherini-Silberstein F, Cento V, Cuypers L, Di Maio VC, Fabeni L, Focà A, Marascio N, Nevens F, Perno CF, Pineda-Peña AC, Schrooten Y, Torti C, Van Laethem K, Vandamme AM, Vrancken B
Publication Year: 2017
Journal: BMC Evolutionary Biology
Link: https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-017-0913-3

In-depth phylogeographic analysis can reveal migration patterns relevant for public health planning. Here, as a model, we focused on the provenance, in the current Italian HCV subtype 1a epidemic, of the NS3 resistance-associated variant (RAV) Q80K, known to interfere with the action of NS3/4A protease inhibitor simeprevir. HCV1a migration patterns were analysed using Bayesian phylodynamic […]
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Serological association between Leishmania infantum and sand fly fever Sicilian (but not Toscana) virus in sheltered dogs from southern Portugal

Authors: Alwassouf S, Ayhan N, Campino L, Charrel RN, Cristóvão JM, Maia C, Pereira A
Publication Year: 2017
Journal: Parasites & Vectors
Link: https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-017-2023-x

Phlebotomine sand fly-borne diseases such as leishmanioses and phleboviruses are emerging threats to animal and public health. Canine leishmaniosis caused by Leishmania infantum is an endemic zoonosis in Portugal. Antibodies to Toscana virus (TOSV) and sand fly fever Sicilian virus (SFSV) were also reported in dogs from the south of the country. The aim of this work […]
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Large cluster outbreaks sustain the HIV epidemic among MSM in Quebec

Authors: Brenner BG, Grossman Z, Hardy I, Ibanescu RI, Moodie E, Otis J, Roger M, Stephens D, Vandamme AM, Wainberg MA
Publication Year: 2017
Journal: AIDS
Link: https://insights.ovid.com/crossref?an=00002030-201703130-00012you

Objective: HIV-1 epidemics among men having sex with men (MSM) remain unchecked despite advances in treatment and prevention paradigms. This study combined viral phylogenetic and behavioural risk data to better understand underlying factors governing the temporal growth of the HIV epidemic among MSM in Quebec (2002-2015). Methods: Phylogenetic analysis of pol sequences was used to […]
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A tool for exploring the dynamics of innovative interventions for public health: the critical event card

Antileishmanial activity of meroditerpenoids from the macroalgae Cystoseira baccata

Implications of hepatitis C virus subtype 1a migration patterns for virus genetic sequencing policies in Italy

Serological association between Leishmania infantum and sand fly fever Sicilian (but not Toscana) virus in sheltered dogs from southern Portugal

Large cluster outbreaks sustain the HIV epidemic among MSM in Quebec

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