GHTM

Global Health and Tropical Medicine

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Home / Publications

Schistosomiasis and Acute Appendicitis

  • Authors: Belo S, Clemente H, Costa S, Figueiredo J, Grácio MA, Lourenco A, Santos A
  • Publication Year: 2014
  • Journal: Acta Médica Portuguesa
  • Link: http://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5150

Acute appendicitis associated to Schistosoma haematobium and S. mansoni infection has been found in patients submitted to urgent appendectomy at the Hospital Américo Boavida in Luanda. Due to the high prevalence and morbidity caused by schistosomiasis (or bilharziasis) in the country, we suspect that the involvement of Schistosoma infection on appendicular pathology could be very frequent, in particular for those individuals more exposed to the parasite transmission.
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Prostate adenocarcinoma associated with prostatic infection due to Schistosoma haematobium. Case report and systematic review

  • Authors: Balaca M, Belo S, Costa A, Figueiredo J, Grácio MA, Nilo B, Richter J
  • Publication Year: 2014
  • Journal: Journal Parasitology Research
  • Link: http://link.springer.com/article/10.1007%2Fs00436-014-4250-9

We describe the first case of a prostate adenocarcinoma associated with prostatic Schistosoma haematobium infection occurring in Angola. Prostate carcinoma was suspected because of high levels of prostate-specific antigen. This observation prompted us to review the literature on schistosomiaisis with respect to genital pathology and prostate cancer.
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Genotypic diversity of environmental Cryptococcus neoformans isolates from Northern Portugal

  • Authors: Ferreira AS, Inácio J, Maduro AP, Martins Mda L, Sampaio A, Silva I, Teles F
  • Publication Year: 2014
  • Journal: Mycoses
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/23848429

The Cryptococcus neoformans/C. gattii species complex members are the main agents of systemic cryptococcosis. This disease is believed to be acquired from the environment via fungal cell inhalation. Often, isolates recovered from environmental and clinical sources have proven to be genotypically similar. We assessed the occurrence of C. neoformans and C. gattii in environmental substrates collected in a Portuguese region.
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Direct detection and differentiation of pathogenic Leptospira species using a multi gene targeted real time PCR approach

  • Authors: Ahmed A, Amaro A, Costa P, Ferreira AS, Harstkeerl RA, Inácio J, Rocha T, Thompson G, Vieira ML
  • Publication Year: 2014
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112312

In this work we describe a novel and simple TaqMan-based multi-gene targeted real-time PCR approach able to detect and differentiate Leptospira interrogans, L. kirschneri, L. borgpeteresenii and L. noguchii, which constitute the veterinary most relevant pathogenic species of Leptospira.
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The early spread and epidemic ignition of HIV-1 in human populations

  • Authors: Arinaminpathy N, Baele G, Bedford T, Faria NR, Lemey P, Peeters M, Pepin J, Posada D, Pybus OG, Rambaut A, Sousa JD, Suchard MA, Tatem AJ, Ward MJ
  • Publication Year: 2014
  • Journal: Science
  • Link: http://www.sciencemag.org/content/346/6205/56.abstract

Thirty years after the discovery of HIV-1, the early transmission, dissemination, and establishment of the virus in human populations remain unclear. Using statistical approaches applied to HIV-1 sequence data from central Africa, we show that from the 1920s Kinshasa (in what is now the Democratic Republic of Congo) was the focus of early transmission and the source of pre-1960 pandemic viruses elsewhere.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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Funding

UID/04413/2025 - DOI: 10.54499/UID/04413/2025

UID/PRR/04413/2025 - DOI: 10.54499/UID/PRR/04413/2025

UID/PRR2/04413/2025 - DOI: 10.54499/UID/PRR2/04413/2025

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