Malaria determining risk factors at the household level in two rural villages of mainland Equatorial Guinea

Authors: Guerra M, de Sousa B, Ndong-Mabale N, Berzosa P, Arez AP
Publication Year: 2018
Journal: Malaria Journal
Link: https://www.ncbi.nlm.nih.gov/pubmed/29776367

BACKGROUND: After the introduction of an artemisinin-based combination therapy, the reduction of prevalence of malaria infections has shown a remarkable progress during the last decade. However due to the lack of a consistent malaria control programme and socioeconomic inequalities, Plasmodium infection is still one of the major cause of disease in Equatorial Guinea, namely in […]
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Plasmodium falciparum genetic diversity in continental Equatorial Guinea before and after introduction of artemisinin based combination therapy

Authors: Arez AP, Berzosa P, de Sousa B, Guerra M, Mendes C, Ndong-Mabale N, Neres R, Salgueiro P
Publication Year: 2017
Journal: Antimicrobial Agents and Chemotherapy
Link: http://aac.asm.org/content/61/1/e02556-15.full%20

Efforts to control malaria may affect malaria parasite genetic variability and drug resistance, the latter of which is associated with genetic events that promote mechanisms to escape drug action. The worldwide spread of drug resistance has been a major obstacle to controlling Plasmodium falciparum malaria, and thus the study of the origin and spread of associated mutations […]
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Filling gaps on ivermectin knowledge: effects on the survival and reproduction of Anopheles aquasalis, a Latin American malaria vector

Authors: Bassat Q, Beltrán TP, Guerra M, Kobylinski KC, Lacerda MV, Lima JBP, Melo GC, Monteiro WM, Pimenta P, Rodriguez I, Sampaio VS, Silva SGM, Silveira H
Publication Year: 2016
Journal: Malaria Journal
Link: https://malariajournal.biomedcentral.com/articles/10.1186/s12936-016-1540-y

Background Strategies designed to advance towards malaria elimination rely on the detection and treatment of infections, rather than fever, and the interruption of malaria transmission between mosquitoes and humans. Mass drug administration with anti-malarials directed at eliminating parasites in blood, either to entire populations or targeting only those with malaria infections, are considered useful strategies […]
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Triosephosphate isomerase gene promoter variation:-5G/A and-8G/A polymorphisms in clinical malaria groups in two African populations

Authors: Arez AP, Fernandes N, Guerra M, Machado P, Manco L, Miranda J
Publication Year: 2015
Journal: Infection Genetics and Evolution
Link: https://www.sciencedirect.com/science/article/pii/S1567134815001057?via%3Dihub

TPI1 promoter polymorphisms occur in high prevalence in individuals from African origin. Malaria-patients from Angola and Mozambique were screened for the TPI1 gene promoter variants rs1800200A>G, (-5G>A), rs1800201G>A, (-8G>A), rs1800202T>G, (-24T>G), and for the intron 5 polymorphism rs2071069G>A, (2262G>A). -5G>A and -8G>A variants occur in 47% and 53% in Angola and Mozambique, respectively while -24T>G […]
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Malaria determining risk factors at the household level in two rural villages of mainland Equatorial Guinea

Plasmodium falciparum genetic diversity in continental Equatorial Guinea before and after introduction of artemisinin based combination therapy

Filling gaps on ivermectin knowledge: effects on the survival and reproduction of Anopheles aquasalis, a Latin American malaria vector

Triosephosphate isomerase gene promoter variation:-5G/A and-8G/A polymorphisms in clinical malaria groups in two African populations

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