Bridging epidemiology with population genetics in a low incidence MSM-driven HIV-1 subtype B epidemic in Central Europe

Authors: Abecasis AB, Karner P, Lunar MM, Pecavar B, Poljak M, Tomazic J, Vandamme AM, Volcansek G, Vovko TD
Publication Year: 2015
Journal: BMC Infectious Diseases
Link: https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-015-0802-6

The HIV-1 epidemic in Slovenia, a small Central European country, has some characteristics that make it an ideal model to study HIV-1 transmission. The epidemic is predominantly affecting men who have sex with men infected with subtype B (89% of all patients), has a low prevalence (less than 1/1000) and is growing slowly. The aim […]
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HIV serostatus knowledge and serostatus disclosure with the most recent anal intercourse partner in a European MSM sample recruited in 13 cities: results from the Sialon-II study

Authors: Alexiev I, Berglund T, Dias SF, Folch C, Gama AF, Gios L, Jones AM, Klavs I, Marcus U, Mirandola M, Naseva E, Niedźwiedzka-Stadnik M, Nöstlinger C, Pitigoi D, Rafila A, Schink SB, Sherriff N, Sialon II Network, Staneková D, Toskin I
Publication Year: 2017
Journal: BMC Infectious Diseases
Link: https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-017-2814-x/open-peer-review

Knowledge of HIV status can be important in reducing the risk of HIV exposure. In a European sample of men-who-have-sex-with-men (MSM), we aimed to identify factors associated with HIV serostatus disclosure to the most recent anal intercourse (AI) partner. We also aimed to describe the impact of HIV serostatus disclosure on HIV exposure risks. During […]
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Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort

Authors: Abecasis AB, Assel M, Bartha I, Luca AD, Müller V, Paredes R, Rosi A, Schülter E, Sloot PMA, Sönner-borg A, Svärd J, Torti C, van de Vijver DC, Van Laethem K, Vandamme AM, Zazzi M
Publication Year: 2013
Journal: BMC Infectious Diseases
Link: http://www.biomedcentral.com/1471-2334/13/537/

Superinfection with drug resistant HIV strains could potentially contribute to compromised therapy in patients initially infected with drug-sensitive virus and receiving antiretroviral therapy. To investigate the importance of this potential route to drug resistance, we developed a bioinformatics pipeline to detect superinfection from routinely collected genotyping data, and assessed whether superinfection contributed to increased drug resistance in a large European cohort of viremic, drug treated patients.
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Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe

Authors: Abecasis AB, Albert J, Åsjö B, Balotta C, Beshkov D, Boucher CA, Camacho RJ, Clotet B, Coughlan S, Frentz D, Griskevicius A, Grossman Z, Hamouda O, Horban A, Jørgensen LB, Kolupajeva T, Korn K, Kostrikis LG, Kücherer C, Liitsola K, Linka M, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Staneková D, Stanojevic M, Struck D, Van de Vijver DA, Van Wijngaerden E, Vercauteren J, Wensing AMJ
Publication Year: 2014
Journal: BMC Infectious Diseases
Link: http://www.biomedcentral.com/1471-2334/14/407

One out of ten newly diagnosed patients in Europe was infected with a virus carrying a drug resistant mutation. We analysed the patterns over time for transmitted drug resistance mutations (TDRM) using data from the European Spread program.
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Bridging epidemiology with population genetics in a low incidence MSM-driven HIV-1 subtype B epidemic in Central Europe

HIV serostatus knowledge and serostatus disclosure with the most recent anal intercourse partner in a European MSM sample recruited in 13 cities: results from the Sialon-II study

Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort

Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe

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