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Global Health and Tropical Medicine

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Home / Archives for Silva-Pedrosa R

Molecular heterogeneity of Rhipicephalus sanguineus sensu lato and screening for Ehrlichia canis in mainland Portugal

  • Autores: Sanches GS, Couto J, Silva-Pedrosa R, Ferrolho J, Santos AS, Santos-Silva MM, Antunes S, Domingos A
  • Ano de Publicação: 2018
  • Journal: Ticks and Tick-Borne Diseases
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/29958827

The present study aimed to expand knowledge regarding the molecular characterization of R. sanguineus s.l. in Portugal and to screen for ticks naturally infected with E. canis. A total of 113 R. sanguineus s.l. were collected questing or attached to domestic and wild animals from the 18 administrative regions of mainland Portugal. All the ticks […]
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Comparative efficacy, toxicity and biodistribution of the liposomal amphotericin B formulations Fungisome®and AmBisome®in murine cutaneous leishmaniasis

  • Autores: Wijnant GJ, Van Bocxlaer K, Yardley V, Harris A, Alavijeh M, Silva-Pedrosa R, Antunes S, Maurício I, Murdan S, Croft SL
  • Ano de Publicação: 2018
  • Journal: International Journal for Parasitology: Drugs and Drug Resistance
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/29673889

Fungisome® (F), a liposomal amphotericin B (AmB) product, is marketed in India as a safe and effective therapeutic for the parasitic infection visceral leishmaniasis. Its potential in the treatment of cutaneous leishmaniasis (CL), a disfiguring form of the disease affecting the skin, is currently unknown. Here, we report the evaluation of the efficacy of F in […]
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The battle between Leishmania and the host immune system at a glance

  • Autores: Laurenti MD, Passero F, Pereira M, Rodrigues A, Santos-Gomes G, Santos-Mateus D, Silva-Pedrosa R, Valério-Bolas A
  • Ano de Publicação: 2016
  • Journal: International Trends in Immunity
  • Link: https://webcache.googleusercontent.com/search?q=cache:GZtE3sdIh7sJ:https://www.researchgate.net/profile/Felipe_Passero/publication/297453064_The_Battle_between_Leishmania_and_the_Host_Immune_System_at_a_Glance/links/56df19c708aee77a15fcf238/The-Battle-between-Leishmania-and-the-Host-Immune-System-at-a-Glance.pdf+&cd=1&hl=en&ct=clnk&gl=pt

Leishmaniasis is a neglected parasitic disease whose diverse clinical manifestations are dependent on the interrelations between intrinsic and extrinsic factors. The infecting species of Leishmania, the parasite’s ability to evade mammal immune response and the host genetic background seems to pre-determine the degree of resistance and sensitivity to infection, regulating the disease outcome. The introduction […]
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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+351 213 652 600
+351 213 632 105

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