A21 HIV-1 sub-subtype F1 outbreak among MSM in Belgium

Authors: Alexiev I, Balotta C, Debaisieux L, Devaux C, Fransen K, García Ribas S, Gomes P, Incardona F, Kaiser R, Lemey P, Paraschiv S, Paredes R, Peeters M, Pineda-Peña AC, Ruelle J, Sayan M, Sönnerborg A, Van den Wijngaert S, Van Laethem K, Van Ranst M, Vancutsem E, Vandamme AM, Verhofstede C, Vinken L
Publication Year: 2017
Journal: Virus Evolution
Link: https://academic.oup.com/ve/article/3/suppl_1/vew036.020/4090767%20

HIV-1 non-B subtype infections have been observed in Belgium since the 1980s. However, subtype B predominates amongst men having sex with men (MSM), whereas other subtypes are mainly associated with sub-Saharan African migrants and heterosexual risk behavior. In the last decade, subtype F1 diagnoses have increased substantially in Belgium, representing 9% of newly diagnosed and […]
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Implications of hepatitis C virus subtype 1a migration patterns for virus genetic sequencing policies in Italy

Authors: Aragri M, Balog D, Ceccherini-Silberstein F, Cento V, Cuypers L, Di Maio VC, Fabeni L, Focà A, Marascio N, Nevens F, Perno CF, Pineda-Peña AC, Schrooten Y, Torti C, Van Laethem K, Vandamme AM, Vrancken B
Publication Year: 2017
Journal: BMC Evolutionary Biology
Link: https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-017-0913-3

In-depth phylogeographic analysis can reveal migration patterns relevant for public health planning. Here, as a model, we focused on the provenance, in the current Italian HCV subtype 1a epidemic, of the NS3 resistance-associated variant (RAV) Q80K, known to interfere with the action of NS3/4A protease inhibitor simeprevir. HCV1a migration patterns were analysed using Bayesian phylodynamic […]
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Zika genomics urgently need standardized and curated reference sequences

Authors: Abecasis AB, Cuypers L, Dallmeier K, Libin P, Pineda-Peña AC, Theys K, Vandamme AM
Publication Year: 2017
Journal: PLoS Pathogens
Link: http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006528

Authors: Abagiu A, Abecasis A, Banica L, Jipa R, Libin P, Neaga E, Nicolae I, Otelea D, Paraschiv S, Pineda-Peña AC, Pingarilho M, Theys K
Publication Year: 2017
Journal: PLoS One
Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185866

Co-infections with HIV and HCV are very frequent among people who inject drugs (PWID). However, very few studies comparatively reconstructed the transmission patterns of both viruses in the same population. We have recruited 117 co-infected PWID during a recent HIV outbreak in Romania. Phylogenetic analyses were performed on HIV and HCV sequences in order to […]
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Sub-Epidemics Explain Localized High Prevalence of Reduced Susceptibility to Rilpivirine in Treatment-Naive HIV-1-Infected Patients: Subtype and Geographic Compartmentalization of Baseline Resistance Mutations

Authors: Abecasis AB, Baele G, Camacho RJ, Gomes P, Pineda-Peña AC, Theys K, Van Laethem K, Vandamme AM
Publication Year: 2016
Journal: AIDS Research and Human Retroviruses
Link: https://www.liebertpub.com/doi/abs/10.1089/aid.2015.0095%20

The latest nonnucleoside reverse transcriptase inhibitor (NNRTI) rilpivirine (RPV) is indicated for human immunodeficiency virus type-1 (HIV-1) patients initiating antiretroviral treatment, but the extent of genotypic RPV resistance in treatment-naive patients outside clinical trials is poorly defined. This retrospective observational study of clinical data from Belgium and Portugal evaluates genotypic information from HIV-1 drug-naive patients […]
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A21 HIV-1 sub-subtype F1 outbreak among MSM in Belgium

Implications of hepatitis C virus subtype 1a migration patterns for virus genetic sequencing policies in Italy

Zika genomics urgently need standardized and curated reference sequences

Epidemic dispersion of HIV and HCV in a population of co-infected Romanian injecting drug users

Sub-Epidemics Explain Localized High Prevalence of Reduced Susceptibility to Rilpivirine in Treatment-Naive HIV-1-Infected Patients: Subtype and Geographic Compartmentalization of Baseline Resistance Mutations

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