Origin and Epidemiological History of HIV-1 CRF14_BG

Authors: Abecasis AB, Barroso H, Bártolo I, Borrego P, Camacho R, Gomes P, McCutchan F, Taveira N
Journal: PLoS One
Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=26&SID=P2WA5hwy5j35Sqjoq2z&page=1&doc=1

Background: CRF14_BG isolates, originally found in Spain, are characterized by CXCR4 tropism and rapid disease progression. This study aimed to identify the origin of CRF14_BG and reconstruct its epidemiological history based on new isolates from Portugal.
Read More

Novel potent metallocenes against liver stage malaria

Authors: Cabrita E, da Cruz FP, Do Rosário VE, Gomes P, Gut J, Matos J, Moreira R, Nogueira F, Prudencio M, Rosenthal PJ
Journal: Antimicrobial Agents and Chemotherapy
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Novel+potent+metallocenes+against+liver+stage+malaria.

Novel conjugates of the antimalarial drug primaquine (compound 1) with ferrocene, named primacenes, have been synthesized and screened for their activities against blood stage and liver stage malaria in vitro and host-vector transmission in vivo.
Read More

Memory B-cell depletion is a feature of HIV-2 infection even in the absence of detectable viremia.

Authors: Baptista AP, Cavaleiro R, Fernandes S, Foxall RB, Gomes P, Marcelino JM, Soares RS, Sousa AE, Taveira N, Tendeiro R, Victorino RM
Journal: AIDS
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Memory+B-cell+depletion+is+a+feature+of+HIV-2+infection+even+in+the+absence+of+detectable+viremia

OBJECTIVE:
Memory B-cell loss has long been recognized as an important contributor to HIV immunodeficiency. HIV-2 infection, which is characterized by a slow rate of progression to AIDS and reduced to undetectable viremia, provides a unique model to investigate B-cell disturbances.
Read More

The SIGLIC system for improving the access to surgery in Portugal.

Authors: Gomes P, Lapão LV
Journal: Electronic Journal of Information Systems Evaluation
Link: https://www.researchgate.net/publication/290541531_The_SIGLIC_system_for_improving_the_access_to_surgery_in_Portugal

This paper describes the design and first results of an information system (SIGLIC) that supports the new integrated management program (SIGA) to improve the access to surgery in Portugal.
Read More

Molecular Epidemiological Analysis of Paired pol/env Sequences from Portuguese HIV Type 1 Patients

Authors: Abecasis AB, Camacho RJ, Carvalho AP, Costa I, Diogo I, Gomes P, Martins A, Portuguese Hiv-1 Resistance Study Group
Journal: AIDS Research and Human Retroviruses
Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=5&SID=P2WA5hwy5j35Sqjoq2z&page=1&doc=1

The advent of new therapeutic approaches targeting env and the search for efficient anti-HIV-1 vaccines make it necessary to identify the number of recombinant forms using genomic regions that were previously not frequently sequenced.
Read More

Origin and Epidemiological History of HIV-1 CRF14_BG

Novel potent metallocenes against liver stage malaria

Memory B-cell depletion is a feature of HIV-2 infection even in the absence of detectable viremia.

The SIGLIC system for improving the access to surgery in Portugal.

Molecular Epidemiological Analysis of Paired pol/env Sequences from Portuguese HIV Type 1 Patients

About GHTM

Contacts

Map