Memory B-cell depletion is a feature of HIV-2 infection even in the absence of detectable viremia.

• Authors: Baptista AP, Cavaleiro R, Fernandes S, Foxall RB, Gomes P, Marcelino JM, Soares RS, Sousa AE, Taveira N, Tendeiro R, Victorino RM
• Journal: AIDS
• Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Memory+B-cell+depletion+is+a+feature+of+HIV-2+infection+even+in+the+absence+of+detectable+viremia

OBJECTIVE:
Memory B-cell loss has long been recognized as an important contributor to HIV immunodeficiency. HIV-2 infection, which is characterized by a slow rate of progression to AIDS and reduced to undetectable viremia, provides a unique model to investigate B-cell disturbances.
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