Bacterial membranes enhance the immunogenicity and protective capacity of the surface exposed tick Subolesin-Anaplasma marginale MSP1a chimeric antigen

Ticks are vectors of diseases that affect humans and animals worldwide. Tick vaccines have been proposed as a cost-effective and environmentally sound alternative for tick control. Recently, the Rhipicephalus microplus Subolesin (SUB)-Anaplasma marginale MSP1a chimeric antigen was produced in Escherichia coli as membrane-bound and exposed protein and used to protect vaccinated cattle against tick infestations. […]
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Tick-Pathogen Interactions and Vector Competence: Identification of Molecular Drivers for Tick-Borne Diseases

Authors: Alberdi P, Antunes S, Ayllón N, Bonnet S, Cabezas-Cruz A, Caracappa S, de la Fuente J, Domingos AG, Estrada-Peña A, Fooks AR, Golovchenko M, Gortazar C, Grubhoffer L, Johnson N, Kocan KM, Mansfield KL, Nijhof AM, Papa A, Rego ROM, Rudenko N, Torina A, Vancova M, Villar M
Publication Year: 2017
Journal: Frontiers in Cellular and Infection Microbiology
Link: https://www.frontiersin.org/articles/10.3389/fcimb.2017.00114/full

Ticks and the pathogens they transmit constitute a growing burden for human and animal health worldwide. Vector competence is a component of vectorial capacity and depends on genetic determinants affecting the ability of a vector to transmit a pathogen. These determinants affect traits such as tick-host-pathogen and susceptibility to pathogen infection. Therefore, the elucidation of […]
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Bacterial membranes enhance the immunogenicity and protective capacity of the surface exposed tick Subolesin-Anaplasma marginale MSP1a chimeric antigen

Tick-Pathogen Interactions and Vector Competence: Identification of Molecular Drivers for Tick-Borne Diseases

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