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Home / Archives for Alberdi P

Tick-Pathogen Interactions and Vector Competence: Identification of Molecular Drivers for Tick-Borne Diseases

  • Authors: Alberdi P, Antunes S, Ayllón N, Bonnet S, Cabezas-Cruz A, Caracappa S, de la Fuente J, Domingos AG, Estrada-Peña A, Fooks AR, Golovchenko M, Gortazar C, Grubhoffer L, Johnson N, Kocan KM, Mansfield KL, Nijhof AM, Papa A, Rego ROM, Rudenko N, Torina A, Vancova M, Villar M
  • Publication Year: 2017
  • Journal: Frontiers in Cellular and Infection Microbiology
  • Link: https://www.frontiersin.org/articles/10.3389/fcimb.2017.00114/full

Ticks and the pathogens they transmit constitute a growing burden for human and animal health worldwide. Vector competence is a component of vectorial capacity and depends on genetic determinants affecting the ability of a vector to transmit a pathogen. These determinants affect traits such as tick-host-pathogen and susceptibility to pathogen infection. Therefore, the elucidation of […]
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Tick capillary feeding for the study of proteins involved in tick-pathogen interactions as potential antigens for the control of tick infestation and pathogen infection

  • Authors: Alberdi P, Antunes S, Bell-Sakyi L, de la Fuente J, Domingos A, Fragkoudis R, Merino O, Moreno-Cid JA, Mosqueda J, Perez de la Lastra JM, Weisheit S
  • Publication Year: 2014
  • Journal: Parasites & Vectors
  • Link: http://www.parasitesandvectors.com/content/7/1/42

Ticks represent a significant health risk to animals and humans due to the variety of pathogens they can transmit during feeding. The traditional use of chemicals to control ticks has serious drawbacks, including the selection of acaricide-resistant ticks and environmental contamination with chemical residues. Vaccination with the tick midgut antigen BM86 was shown to be a good alternative for cattle tick control. However, results vary considerably between tick species and geographic location.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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