GHTM

Global Health and Tropical Medicine

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Measuring Efflux and Permeability in Mycobacteria – chapter of «Mycobacteria Protocols»

ABSTRACT Mycobacteria are intrinsically resistant to most antimicrobials, which is generally attributed to the impermeability of their cell wall that considerably limits drug uptake. Moreover, like in other pathogenic bacteria, active efflux systems have been widely characterized from diverse mycobacterial species in laboratory conditions, showing that they can promote resistance by extruding noxious compounds prior […]
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Leishmaniases in the European Union and Neighboring Countries

DISPATCH ABSTRACT A questionnaire survey of animal and human health authorities in Europe revealed that leishmaniases are not notifiable in all countries with autochthonous cases. Few countries implement surveillance and control targeting both animal and human infections. Leishmaniases are considered emergent diseases in most countries, and lack of resources is a challenge for control.   […]
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Leishmania infection in cats and feline leishmaniosis: An updated review with a proposal of a diagnosis algorithm and prevention guidelines

Leishmania infection in cats and feline leishmaniosis: An updated review with a proposal of a diagnosis algorithm and prevention guidelines   Highlights A comprehensive review on epidemiology, immunopathogenesis, diagnosis, treatment, and prevention of feline leishmaniosis. An algorithm for assisting medical diagnosis of leishmaniosis in cats is suggested. Guidelines for the prevention of Leishmania infection in […]
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Artemether-lumefantrine treatment failure of uncomplicated Plasmodium falciparum malaria in travellers coming from Angola and Mozambique

Artemether-lumefantrine treatment failure of uncomplicated Plasmodium falciparum malaria in travellers coming from Angola and Mozambique   Highlights Artemether-lumefantrine (AL) treatment failure of imported malaria in Portugal AL treatment failure in the presence of wild-type pfk13 and pfmdr1 Is the standard 3-day course of AL sufficient to ensure parasite clearance? AL increasing treatment failures urges closer […]
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Malaria prevention knowledge, attitudes, and practices in Zambezia Province, Mozambique

Malaria prevention knowledge, attitudes, and practices in Zambezia Province, Mozambique   Abstract Background: In Mozambique, socio-economic and cultural factors influence the wide adoption of disease preventive measures that are relevant for malaria control strategies to promote early recognition of disease, prompt seeking of medical care, sleeping under insecticide-treated nets (ITNs), and taking intermittent preventive treatment […]
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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Rua da Junqueira, 100
1349-008 Lisboa
Portugal

+351 213 652 600

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