Measuring Efflux and Permeability in Mycobacteria – chapter of «Mycobacteria Protocols»
- Autores: Liliana Rodrigues, José A Aínsa, Miguel Viveiros
- Ano de Publicação: 2021
- Journal: Mycobacteria Protocols, 231-245, part of the book series, Methods in Molecular Biology, 2314
- Link: https://doi.org/10.1007/978-1-0716-1460-0_9
ABSTRACT Mycobacteria are intrinsically resistant to most antimicrobials, which is generally attributed to the impermeability of their cell wall that considerably limits drug uptake. Moreover, like in other pathogenic bacteria, active efflux systems have been widely characterized from diverse mycobacterial species in laboratory conditions, showing that they can promote resistance by extruding noxious compounds prior […]
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