GHTM

Global Health and Tropical Medicine

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Home / Archives for Plos Neglected Tropical Diseases

Mucosal Leishmaniasis caused by Leishmania (Viannia) braziliensis and Leishmania (Viannia) guyanensis in the Brazilian Amazon.

  • Authors: Amato V, Barbosa Md, Coelho LI, Ferreira LC, Gama P, Guerra JA, Moura A, Prestes SR, Silveira H
  • Journal: Plos Neglected Tropical Diseases
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Mucosal+Leishmaniasis+caused+by+Leishmania+(Viannia)+braziliensis+and+Leishmania+(Viannia)+guyanensis+in+the+Brazilian+Amazon

BACKGROUND:
Leishmania (Viannia) braziliensis is a parasite recognized as the most important etiologic agent of mucosal leishmaniasis (ML) in the New World. In Amazonia, seven different species of Leishmania, etiologic agents of human Cutaneous Leishmaniasis, have been described. Isolated cases of ML have been described for several different species of Leishmania: L. (V.) panamensis, L. (V.) guyanensis and L. (L.) amazonensis.
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Multilocus sequence typing (MLST) for lineage assignment and high resolution diversity studies in Trypanosoma cruzi.

  • Authors: Acosta N, Bhattacharyya T, Carrasco HJ, Diosque P, Lewis MD, Llewellyn MS, Mauricio IL, Messenger LA, Miles MA, Yeo M
  • Journal: Plos Neglected Tropical Diseases
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Multilocus+sequence+typing+(MLST)+for+lineage+assignment+and+high+resolution+diversity+studies+in+Trypanosoma+cruzi

BACKGROUND:
Multilocus sequence typing (MLST) is a powerful and highly discriminatory method for analysing pathogen population structure and epidemiology. Trypanosoma cruzi, the protozoan agent of American trypanosomiasis (Chagas disease), has remarkable genetic and ecological diversity. A standardised MLST protocol that is suitable for assignment of T. cruzi isolates to genetic lineage and for higher resolution diversity studies has not been developed.
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Research priorities for neglected infectious diseases in Latin America and the Caribbean region

  • Authors: Arevalo J, Boelaert M, Carrasco HJ, Correa-Oliveira R, Do Rosário V, Garcia L, Gotuzzo E, Gyorkos TW, Herrera S, Kalergis AM, Kouri G, Larraga V, Lutumba P, Macias Garcia MA, Manrique-Saide PC, Modabber F, Nieto A, Olesen OF, Pluschke G, Robello C, Rojas de Arias A, Rumbo M, Santos Preciado JI, Sundar S, Torres J, Torrico F, Van der Stuyft P, Victoir K
  • Journal: Plos Neglected Tropical Diseases
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/21049009

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Comparative microsatellite typing of new world leishmania infantum reveals low heterogeneity among populations and its recent old world origin.

  • Authors: Alam MZ, Cupolillo E, Feliciangeli MD, Ferreira GE, Kuhls K, Mauricio IL, Miles MA, Oddone R, Schönian G, Wirth T
  • Journal: Plos Neglected Tropical Diseases
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Comparative+microsatellite+typing+of+new+world+Leishmania+infantum+reveals+low+heterogeneity+among+populations+and+its+recent+old+world+origin.

Leishmania infantum (syn. L. chagasi) is the causative agent of visceral leishmaniasis (VL) in the New World (NW) with endemic regions extending from southern USA to northern Argentina.
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Vaccines for the leishmaniases: proposals for a research agenda.

  • Authors: Costa CHN, Peters NC, Maruyama SR, de Brito EC, Santos IK
  • Journal: Plos Neglected Tropical Diseases
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Vaccines+for+the+Leishmaniases%3A+Proposals+for+a+research+agenda.

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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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Funding

UID/04413/2025 - DOI: 10.54499/UID/04413/2025

UID/PRR/04413/2025 - DOI: 10.54499/UID/PRR/04413/2025

UID/PRR2/04413/2025 - DOI: 10.54499/UID/PRR2/04413/2025

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