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Home / Archives for International Journal for Parasitology

Lungworms and gastrointestinal parasites of domestic cats: a European perspective

  • Autores: Annoscia G, Beugnet F, Brianti E, Cantacessi C, Capelli G, Cardoso L, Cavalera MA, Colella V, Farkas R, Giannelli A, Halos L, Hinney B, Joachim A, Kirkova Z, Knaus M, Latrofa MS, Losson B, Madeira de Carvalho L, Maia C, Margarida Alho A, Mihalca AD, Mircean V, Miró G, Napoli E, Otranto D, Papadopoulos E, René-Martellet M, Schnyder M, Tamponi C, Varcasia A
  • Ano de Publicação: 2017
  • Journal: International Journal for Parasitology
  • Link: https://www.sciencedirect.com/science/article/pii/S0020751917301017

With the exception of Aelurostrongylus abstrusus, feline lungworms have been poorly studied. Information on their distribution is patchy and mostly limited to case reports. In this study, the occurrence of feline lungworms and co-infecting gastrointestinal parasites has been investigated in 12 European countries (i.e. Austria, Belgium, Bulgaria, France, Greece, Hungary, Italy, Portugal, Romania, Spain, Switzerland […]
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Genetic structure of Phlebotomus (Larroussius) ariasi populations, the vector of Leishmania infantum in the western Mediterranean: epidemiological implications

  • Autores: Afonso MO, Alves-Pires C, Barón SD, Bounamous A, Depaquit J, Díaz V, Franco FA, Gállego M, Gálvez R, Guernaoui S, Martín-Sánchez J, Molina R, Morales-Yuste M, Morillas-Márquez F, Pesson B
  • Journal: International Journal for Parasitology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Genetic+structure+of+Phlebotomus+(Larroussius)+ariasi+populations%2C+the+vector+of+Leishmania+infantum+in+the+western+Mediterranean%3A+Epidemiological+implications

In recent years there has been growing interest in analyzing the geographical variations between populations of different Phlebotomus spp. by comparing the sequences of various genes. However, little is known about the genetic structure of Phlebotomus ariasi. In this study, we were able to sequence a fragment of the mitochondrial Cyt b gene in 133 […]
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Microsporidia as emerging pathogens and the implication for public health: a 10-year study on HIV-positive and -negative patients.

  • Autores: Antunes F, Lobo ML, Matos O, Xiao L
  • Journal: International Journal for Parasitology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Microsporidia+as+emerging+pathogens+and+the+implication+for+public+health%3A+A+10-year+study+on+HIV-positive+and+-negative+patients.

Despite recent advances in the understanding and diagnosis of emerging microsporidian pathogens, more research is necessary to elucidate their complex epidemiology. In fact, studies that reflect true human-infecting microsporidian prevalence are still inadequate. The present 10-year study was undertaken to examine the occurrence of Microsporidia in 1989 stools, 69 urine and 200 pulmonary specimens from HIV-positive and HIV-negative patients using PCR and DNA sequencing.
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Functional genomics studies of Rhipicephalus (Boophilus) annulatus ticks in response to infection with the cattle protozoan parasite, Babesia bigemina.

  • Autores: Almazán C, Antunes S, de la Fuente J, Do Rosário V, Domingos A, Galindo RC, Golovchenko M, Grubhoffer L, Rudenko N, Shkap V
  • Journal: International Journal for Parasitology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Functional+genomics+studies+of+Rhipicephalus+(Boophilus)+annulatus+ticks+in+response+to+infection+with+the+cattle+protozoan+parasite%2C+Babesia+bigemina

Ticks are obligate haematophagous ectoparasites of wild and domestic animals as well as humans, considered to be second worldwide to mosquitoes as vectors of human diseases, but the most important vectors of disease-causing pathogens in domestic and wild animals. Babesia spp. are tick-borne pathogens that cause a disease called babesiosis in a wide range of animals and in humans.
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Whole genome re-sequencing identifies a mutation in an ABC transporter (mdr2) in a Plasmodium chabaudi clone with altered susceptibility to antifolate drugs?

  • Autores: Cravo P, Henriques G, Hunt P, Martinelli A
  • Journal: International Journal for Parasitology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Whole+genome+re-sequencing+identifies+a+mutation+in+an+ABC+transporter+(mdr2)+in+a+Plasmodium+chabaudi+clone+with+altered+susceptibility+to+antifolate+drugs%3F.

In malaria parasites, mutations in two genes of folate biosynthesis encoding dihydrofolate reductase (dhfr) and dihydropteroate synthase (dhps) modify responses to antifolate therapies which target these enzymes.
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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