Cough-aerosol cultures of Mycobacterium tuberculosis in the prediction of outcomes after exposure. A household contact study in Brazil
- Authors: Acuña-Villaorduña C, Dietze R, Ellner JJ, Fennelly KP, Gaeddert M, Hadad DJ, Jones-López EC, Marques-Rodrigues P, Palaci M, Schmidt-Castellani LG, White LF
- Publication Year: 2018
- Journal: PLoS One
- Link: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206384
Background Mycobacterium tuberculosis cultures of cough-generated aerosols from patients with pulmonary tuberculosis (TB) are a quantitative method to measure infectiousness and to predict secondary outcomes in exposed contacts. However, their reproducibility has not been established. Objective To evaluate the predictive value of colony-forming units (CFU) of M. tuberculosis in cough aerosols on secondary infection and disease in household contacts […]
Read More