Canine neutrophils activate effector mechanisms in response to Leishmania infantum

Authors: Alexandre-Pires G, da Fonseca IP, Martins C, Passero F, Pereira M, Rocha H, Rodrigues A, Santos A, Santos M, Santos-Gomes G, Santos-Mateus D, Tomas A, Valério-Bolas A
Publication Year: 2017
Journal: Veterinary Parasitology
Link: https://www.ncbi.nlm.nih.gov/pubmed/29173534

Canine leishmaniosis caused by L. infantum is a severe zoonotic disease. Although macrophages are the definitive host cells, neutrophils are the first cells to encounter the parasite soon after its inoculation in the dermis by the phlebotomine vector. To study the interaction of dog neutrophils and L. infantum promastigotes, blood neutrophils were isolated from healthy […]
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Canine leishmaniosis. Modulation of macrophage/lymphocyte interactions by L. infantum.

Authors: Alexandre-Pires G, Cartaxeiro C, da Fonseca IP, de Brito TV, Diaz S, Martins C, Rodrigues A, Santos-Gomes GM, Silva MJ
Journal: Veterinary Parasitology
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Canine+leishmaniosis.+Modulation+of+macrophage%2Flymphocyte+interactions+by+L.+infantum.

Canine leishmaniosis, caused by Leishmania infantum, is a systemic disease with variable clinical signs and a progressive evolution. This disease is characterized by impaired T cell-mediated immune response, which has been associated with disease chronicity and high mortality. Protective immunity against leishmaniosis is thought to be mediated by T cell and cytokine production.
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Canine leishmaniasis. Immunophenotypic profile of leukocytes in different compartments of symptomatic, asymptomatic and treated dogs

Canine visceral leishmaniasis (CanL) is an emerging disease, expanding in various parts of the world. The infection caused by Leishmania, an intracellular protozoan parasite, can show different clinical manifestations, from asymptomatic or subclinical to symptomatic dogs, in which a wide spectrum of clinical signs is evident.
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Cytokine Gene Expression in the Tissues of Dogs Infected by Leishmania infantum

Authors: Alexandre-Pires G, Alves LC, Barbosa AMG, da Fonseca IP, de Brito TV, Marques C, Rodrigues OR, Santos-Gomes GM, Soares-Clemente M
Journal: Journal of Comparative Pathology
Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=21&SID=P2WA5hwy5j35Sqjoq2z&page=1&doc=1

Canine leishmaniosis (CanL) caused by the protozoan parasite Leishmania infantum is a chronic systemic disease that is endemic in certain parts of the world. The domestic dog is the most important reservoir of L. infantum and is the main source of infection for other animals and for the human population.
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Canine neutrophils activate effector mechanisms in response to Leishmania infantum

Canine leishmaniosis. Modulation of macrophage/lymphocyte interactions by L. infantum.

Canine leishmaniasis. Immunophenotypic profile of leukocytes in different compartments of symptomatic, asymptomatic and treated dogs

Cytokine Gene Expression in the Tissues of Dogs Infected by Leishmania infantum

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