New insights on taxonomy, phylogeny and population genetics of Leishmania (Viannia) parasites based on multilocus sequence analysis.

Authors: Boité MC, Cupolillo E, Mauricio IL, Miles MA
Journal: PLoS Negl Trop Dis
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=New+insights+on+taxonomy%2C+phylogeny+and+population+genetics+of+Leishmania+(Viannia)+parasites+based+on+multilocus+sequence+analysis

The Leishmania genus comprises up to 35 species, some with status still under discussion. The multilocus sequence typing (MLST)–extensively used for bacteria–has been proposed for pathogenic trypanosomatids. For Leishmania, however, a detailed analysis and revision on the taxonomy is still required.
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Population structure and evidence for bothclonality and recombination among Brazilian strains of the subgenus Leishmania(Viannia)

Authors: Boité MC, Cupolillo E, Kuhls K, Maurício I, Mello MN, Miles M, Schönian G, Schweynoch C, Silva SO, Wirth T
Journal: PLoS Negleted Tropical Diseases
Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814519/

Parasites of the subgenus Leishmania (Viannia) cause varying clinical symptoms ranging from cutaneous leishmaniases (CL) with single or few lesions, disseminated CL (DL) with multiple lesions to disfiguring forms of mucocutaneous leishmaniasis (MCL). In this population genetics study, 37 strains of L. (V.) guyanensis, 63 of L. (V.) braziliensis, four of L. (V.) shawi, six of L. (V.) lainsoni, seven of L. (V.) naiffi, one each of L. (V.) utingensis and L. (V.) lindenbergi, and one L. (V.) lainsoni/L. naiffi hybrid from different endemic foci in Brazil were examined for variation at 15 hyper-variable microsatellite markers.
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Comparative microsatellite typing of new world leishmania infantum reveals low heterogeneity among populations and its recent old world origin.

Authors: Alam MZ, Cupolillo E, Feliciangeli MD, Ferreira GE, Kuhls K, Mauricio IL, Miles MA, Oddone R, Schönian G, Wirth T
Journal: Plos Neglected Tropical Diseases
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Comparative+microsatellite+typing+of+new+world+Leishmania+infantum+reveals+low+heterogeneity+among+populations+and+its+recent+old+world+origin.

Leishmania infantum (syn. L. chagasi) is the causative agent of visceral leishmaniasis (VL) in the New World (NW) with endemic regions extending from southern USA to northern Argentina.
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New insights on taxonomy, phylogeny and population genetics of Leishmania (Viannia) parasites based on multilocus sequence analysis.

Population structure and evidence for bothclonality and recombination among Brazilian strains of the subgenus Leishmania(Viannia)

Comparative microsatellite typing of new world leishmania infantum reveals low heterogeneity among populations and its recent old world origin.

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