Direct detection by the xpert MTB/RIF assay and characterization of multi and poly drug- resistant tuberculosis in Guinea-Bissau, West Africa

Authors: Armada A, Colombatti R, Gomes VF, Machado D, Mane M, Martins E, Ponce G, Rabna P, Ramos J, Sanca L, Vieira F
Publication Year: 2015
Journal: PLoS One
Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127536%20

This study aimed to evaluate the usefulness of the Xpert MTB/RIF assay for the rapid direct detection of M. tuberculosis complex (MTBC) strains and rifampicin resistance associated mutations in a resource-limited setting such as Guinea-Bissau and its implications in the management of tuberculosis (TB) and drug resistant tuberculosis, complementing the scarce information on resistance and […]
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Lack of evidence for the selection of E138 mutations by first-generation non-nucleoside reverse transcriptase inhibitors in patients infected with HIV-1 non-B subtypes

Authors: Abecasis AB, Theys K, Van Laethem K
Publication Year: 2015
Journal: AIDS
Link: https://insights.ovid.com/pubmed?pmid=25909833

Understanding the mechanisms and predictors of drug resistance development to HIV-1 antiretroviral therapy (ART) is a key challenge to further improve HIV-1 treatment strategies and prevent epidemic spread. The extensive genetic diversity characterizing the HIV-1 pandemic, classified into groups, subtypes and recombinants, has been shown to affect viral escape from drug-selective pressure and influence treatment […]
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Onchocerciasis caused by Onchocerca lupi: an emerging zoonotic infection. Systematic review

Authors: Grácio AJ, Grácio MA, Komnenou AT, Richter J
Publication Year: 2015
Journal: Parasitology Research
Link: https://link.springer.com/article/10.1007%2Fs00436-015-4535-7

Globalization has increased circulation of people, their food, livestock and pets in the world, and changes in the environment, climate and human behaviour have led to the rapid expansion of emerging infections throughout the world. One of the reasons of a new pathogen affecting humans is the passage from an animal to a human being. […]
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Training laypersons and hospital personnel in basic resuscitation techniques: An approach to impact the global trauma burden in mozambique

Authors: Gonzaléz-Calvo L, McQueen K, Merchant A, Moon TD, Outhay M, Sidat M, Taibo CL
Publication Year: 2015
Journal: World Journal of Surgery
Link: https://link.springer.com/article/10.1007%2Fs00268-015-2966-z%20

Over half of prehospital deaths in low-income countries are the result of airway compromise, respiratory failure, or uncontrolled hemorrhage; all three conditions can be addressed using simple first-aid measures. For both hospital personnel and laypersons, a basic trauma resuscitation training in modified ABCD (airway, breathing, circulation, disability) techniques can be easily learned and applied to […]
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Southern Africa: the Highest Priority Region for HIV Prevention and Care Interventions

Authors: Sheldon EK, Sidat M, Vermund SH
Publication Year: 2015
Journal: Current HIV/AIDS Reports
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536916/%20

The global HIV pandemic began to expand rapidly in southern Africa a decade later than was noted in central Africa, Europe, the Caribbean, and North America. Multiple factors played a role in this rapid expansion which led Southern Africa to become the most heavily afflicted region for HIV/AIDS globally. In this issue of Current HIV/AIDS […]
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Direct detection by the xpert MTB/RIF assay and characterization of multi and poly drug- resistant tuberculosis in Guinea-Bissau, West Africa

Lack of evidence for the selection of E138 mutations by first-generation non-nucleoside reverse transcriptase inhibitors in patients infected with HIV-1 non-B subtypes

Onchocerciasis caused by Onchocerca lupi: an emerging zoonotic infection. Systematic review

Training laypersons and hospital personnel in basic resuscitation techniques: An approach to impact the global trauma burden in mozambique

Southern Africa: the Highest Priority Region for HIV Prevention and Care Interventions

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