Probing the aurone scaffold against Plasmodium falciparum: Design, synthesis and antimalarial activity

Authors: Carrasco MP, dos Santos DJVA, Gois A, Gonçalves L, Guedes RC, Gut J, Haenscheid T, Machado M, Moreira R, Newton AS, Nogueira F, Rosenthal PJ
Publication Year: 2014
Journal: European Journal of Medicinal Chemistry
Link: http://www.ncbi.nlm.nih.gov/pubmed/24813880

A library comprising 44 diversely substituted aurones derivatives was synthesized by straightforward aldol condensation reactions of benzofuranones and the appropriately substituted benzaldehydes. Microwave enhanced synthesis using palladium catalyzed protocols was introduced as a powerful strategy for extending the chemical space around the aurone scaffold.
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Development of a monoclonal antibody TAS-ELISA assay for detection of Phaeomoniella chlamydospora

Authors: Cardoso F, Nascimento T, Oliveira H
Publication Year: 2014
Journal: Phytopathologia Mediterranea
Link: http://www.fupress.net/index.php/pm/article/view/11860

A monoclonal antibody-based triple antibody sandwich (TAS) enzyme-linked immunosorbent assay (ELISA) was developed to specifically detect Pa. chlamydospora from grapevine wood tissues. This assay could be especially useful for large-scale application in nurseries, to ensure Pa. chlamydospora-free grapevine stocks, and thus contributing to the production of healthy propagation material.
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Prominent intraspecific genetic divergence within Anopheles gambiae sibling species triggered by habitat discontinuities across a riverine landscape

Authors: Caputo B, Caputo FP, Conway DJ, Della Torre A, Dia I, Hamid-Adiamoh M, Jawara M, Konate L, Nwakanma D, Oriero EC, Petrarca V, Pinto J
Publication Year: 2014
Journal: Molecular Ecology
Link: http://onlinelibrary.wiley.com/doi/10.1111/mec.12866/abstract

The Anopheles gambiae complex of mosquitoes includes malaria vectors at different stages of speciation, whose study enables a better understanding of how adaptation to divergent environmental conditions leads to evolution of reproductive isolation. We investigated the population genetic structure of closely related sympatric taxa that have recently been proposed as separate species (An. coluzzii and An. gambiae), sampled from diverse habitats along the Gambia river in West Africa.
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Macroclimate Determines the Global Range Limit of Aedes aegypti

Authors: Capinha C, Rocha J, Sousa CA
Publication Year: 2014
Journal: Ecohealth
Link: http://www.ncbi.nlm.nih.gov/pubmed/24643859

Aedes aegypti is the main vector of dengue and a number of other diseases worldwide. Because of the domestic nature of this mosquito, the relative importance of macroclimate in shaping its distribution has been a controversial issue. We have captured here the worldwide macroclimatic conditions occupied by A. aegypti in the last century. We assessed the ability of this information to predict the species’ observed distribution using supra-continental spatially-uncorrelated data.
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Brazil and the Shifting Consensus on Development Co-Operation: Salutary Diversions from the ‘Aid-Effectiveness’ Trail?

Authors: Cabral L, Russo G, Weinstock J
Publication Year: 2014
Journal: Development Policy Review
Link: http://onlinelibrary.wiley.com/doi/10.1111/dpr.12050/abstract;jsessionid=3317854DB3D2D6B68C04FD47630308B9.f01t03

This article draws on research on Brazil’s technical co-operation and its health dimension to compare the Brazilian model with established aid-effectiveness’ principles and to discuss the appropriateness of the latter as standards against which to appraise emerging donors’ co-operation.
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Probing the aurone scaffold against Plasmodium falciparum: Design, synthesis and antimalarial activity

Development of a monoclonal antibody TAS-ELISA assay for detection of Phaeomoniella chlamydospora

Prominent intraspecific genetic divergence within Anopheles gambiae sibling species triggered by habitat discontinuities across a riverine landscape

Macroclimate Determines the Global Range Limit of Aedes aegypti

Brazil and the Shifting Consensus on Development Co-Operation: Salutary Diversions from the ‘Aid-Effectiveness’ Trail?

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