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Home / Archives for Conway DJ

Remarkable diversity of intron-1 of the para voltage-gated sodium channel gene in an Anopheles gambiae/Anopheles coluzzii hybrid zone

  • Autores: Caputo B, Conway DJ, Della Torre A, Fanello C, Mancini E, Nwakanma DC, Petrarca V, Pinto J, Santolamazza F, Weetman D
  • Ano de Publicação: 2015
  • Journal: Malaria Journal
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/25604888

BACKGROUND: Genomic differentiation between Anopheles gambiae and Anopheles coluzzii–the major malaria vectors in sub-Saharan Africa–is localized into large “islands” toward the centromeres of chromosome-X and the two autosomes. Linkage disequilibrium between these genomic islands was first detected between species-specific polymorphisms within ribosomal DNA genes (IGS-rDNA) on the X-chromosome and a single variant at position 702 […]
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The “far-west” of Anopheles gambiae molecular forms.

  • Autores: Besansky NJ, Caputo B, Conway DJ, Della Torre A, Jaenson T, Jawara M, Mancini E, Nwakanma DC, Palsson K, Petrarca V, Santolamazza F, Vicente JL, White BJ
  • Journal: PLoS One
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=The+%E2%80%9Cfar-west%E2%80%9D+of+Anopheles+gambiae+molecular+forms

The main Afrotropical malaria vector, Anopheles gambiae sensu stricto, is undergoing a process of sympatric ecological diversification leading to at least two incipient species (the M and S molecular forms) showing heterogeneous levels of divergence across the genome.
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Prominent intraspecific genetic divergence within Anopheles gambiae sibling species triggered by habitat discontinuities across a riverine landscape

  • Autores: Caputo B, Caputo FP, Conway DJ, Della Torre A, Dia I, Hamid-Adiamoh M, Jawara M, Konate L, Nwakanma D, Oriero EC, Petrarca V, Pinto J
  • Ano de Publicação: 2014
  • Journal: Molecular Ecology
  • Link: http://onlinelibrary.wiley.com/doi/10.1111/mec.12866/abstract

The Anopheles gambiae complex of mosquitoes includes malaria vectors at different stages of speciation, whose study enables a better understanding of how adaptation to divergent environmental conditions leads to evolution of reproductive isolation. We investigated the population genetic structure of closely related sympatric taxa that have recently been proposed as separate species (An. coluzzii and An. gambiae), sampled from diverse habitats along the Gambia river in West Africa.
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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