The heterogeneous ribonuclear protein C interacts with the hepatitis delta virus small antigen.

Authors: Casaca A, Cunha C, da Cruz e Silva E, Fardilha M
Journal: Virology Journal
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=The+heterogeneous+ribonuclear+protein+C+interacts+with+the+hepatitis+delta+virus+small+antigen

BACKGROUND:
Hepatitis delta virus (HDV) is considered to be a satellite virus of the Hepatitis B virus. The genome consists of a 1679 nt ssRNA molecule in which a single ORF was identified.
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Simultaneous RNA quantification of human and retroviral genomes reveals intact interferon signaling in HTLV-1-infected CD4+ T cell lines.

Authors: Bittencourt A, Farré L, Galvão-Castro B, Gotuzzo E, Khouri R, López G, Moens B, Pannecouque C, Talledo M, Van Weyenbergh J, Vandamme AM
Journal: Virology Journal
Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Simultaneous+RNA+quantification+of+human+and+retroviral+genomes+reveals+intact+interferon+signaling+in+HTLV-1-infected+CD4%2B+T+cell+lines.

BACKGROUND:
IFN-α contributes extensively to host immune response upon viral infection through antiviral, pro-apoptotic, antiproliferative and immunomodulatory activities. Although extensively documented in various types of human cancers and viral infections, controversy exists in the exact mechanism of action of IFN-α in human immunodeficiency virus type 1 (HIV-1) and human T-lymphotropic virus type 1 (HTLV-1) retroviral infections.
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The heterogeneous ribonuclear protein C interacts with the hepatitis delta virus small antigen.

Simultaneous RNA quantification of human and retroviral genomes reveals intact interferon signaling in HTLV-1-infected CD4+ T cell lines.

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