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Global Health and Tropical Medicine

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A novel nested polymerase chain reaction assay targeting Plasmodium mitochondrial DNA in field-collected Anopheles mosquitoes

Sensitive techniques for the detection of Plasmodium (Aconoidasida: Plasmodiidae) sporozoites in field-collected malaria vectors are essential for the correct assessment of risk for malaria transmission. A real-time polymerase chain reaction (RT-PCR) protocol targeting Plasmodium mtDNA proved to be much more sensitive in detecting sporozoites in mosquitoes than the widely used enzyme-linked immunosorbent assay targeting Plasmodium […]
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The study of arboviroses transmitted by vectors in IHMT

The study of vector-borne diseases has always been an area of interest of the Instituto do Higiene do Medicina Tropical (IHMT). After the eradication of malaria in Portugal, the activity of IHMT in this field of knowledge focused mainly on the study of these diseases in tropical and subtropical regions. However with the (re)emergence of […]
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Limited genomic divergence between intraspecific forms of Culex pipiens under different ecological pressures

Divergent selection can be a major driver of ecological speciation. In insects of medical importance, understanding the speciation process is both of academic interest and public health importance. In the West Nile virus vector Culex pipiens, intraspecific pipiens and molestus forms vary in ecological and physiological traits. Populations of each form appear to share recent common […]
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Microencapsulation of citronella oil for solar-activated controlled release as an insect repellent

This study investigates the functionalization of titanium dioxide nanoparticles on the surface of polymeric microcapsules as a mean to control the release of encapsulated citronella through solar radiation. This allows for the release of a mosquito repellent without human intervention, as the sunlight works as a release activator. The TiO2 nanoparticles were synthetized using a […]
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Climate change and mosquito-borne disease

Ecology, development, behaviour, and survival of mosquitoes as well as the transmission dynamic of pathogens, strongly depend on climatic factors. Models have been developed to predict forthcoming mosquito-borne diseases scenarios based on estimations of future climate patterns. However, the complex interplay of climate variables with the mosquito-host-pathogen systems rend the overall effect of the climate […]
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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