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Home / Archives for Wilding CS

Limited genomic divergence between intraspecific forms of Culex pipiens under different ecological pressures

  • Authors: Gomes B, Wilding CS, Weetman D, Sousa CA, Novo MT, Savage H, Almeida APG, Pinto J, Donnelly MJ
  • Publication Year: 2015
  • Journal: BMC Evolutionary Biology
  • Link: https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-015-0477-z

Divergent selection can be a major driver of ecological speciation. In insects of medical importance, understanding the speciation process is both of academic interest and public health importance. In the West Nile virus vector Culex pipiens, intraspecific pipiens and molestus forms vary in ecological and physiological traits. Populations of each form appear to share recent common […]
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Gene flow-dependent genomic divergence between Anopheles gambiae M and S forms.

  • Authors: Donnelly MJ, Steen K, Weetman D, Wilding CS, Pinto J
  • Journal: Molecular Biology and Evolution
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Gene+Flow-Dependent+Genomic+Divergence+between+Anopheles+gambiae+M+and+S+Forms.

Anopheles gambiae sensu stricto exists as two often-sympatric races termed the M and S molecular forms, characterized by fixed differences at an X-linked marker. Extreme divergence between M and S forms at pericentromeric “genomic islands” suggested that selection on variants therein could be driving interform divergence in the presence of ongoing gene flow, but recent work has detected much more widespread genomic differentiation.
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Gene flow-dependent genomic divergence between Anopheles gambiae M and S forms.

  • Authors: Donnelly MJ, Steen K, Weetman D, Wilding CS, Pinto J
  • Journal: Molecular Biology and Evolution
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Gene+flow-dependent+genomic+divergence+between+Anopheles+gambiae+M+and+S+forms

Anopheles gambiae sensu stricto exists as two often-sympatric races termed the M and S molecular forms, characterized by fixed differences at an X-linked marker. Extreme divergence between M and S forms at pericentromeric “genomic islands” suggested that selection on variants therein could be driving interform divergence in the presence of ongoing gene flow, but recent work has detected much more widespread genomic differentiation.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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