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Home / Archives for Schmit JC

Increase in transmitted resistance to non-nucleoside reverse transcriptase inhibitors among newly diagnosed HIV-1 infections in Europe

  • Authors: Abecasis AB, Albert J, Åsjö B, Balotta C, Beshkov D, Boucher CA, Camacho RJ, Clotet B, Coughlan S, Frentz D, Griskevicius A, Grossman Z, Hamouda O, Horban A, Jørgensen LB, Kolupajeva T, Korn K, Kostrikis LG, Kücherer C, Liitsola K, Linka M, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Staneková D, Stanojevic M, Struck D, Van de Vijver DA, Van Wijngaerden E, Vercauteren J, Wensing AMJ
  • Publication Year: 2014
  • Journal: BMC Infectious Diseases
  • Link: http://www.biomedcentral.com/1471-2334/14/407

One out of ten newly diagnosed patients in Europe was infected with a virus carrying a drug resistant mutation. We analysed the patterns over time for transmitted drug resistance mutations (TDRM) using data from the European Spread program.
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Patterns of Transmitted HIV drug resistance in Europe vary by risk group

  • Authors: Abecasis A, Albert J, Åsjö B, Balotta C, Bergin C, Beshkov D, Boucher C, Camacho R, Clotet B, Frentz D, Griskevicius A, Grossman Z, Hamouda O, Horban A, Jørgensen L, Kolupajeva T, Korn K, Kostrikis L, Kücherer C, Linka KL, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Programme AW, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Staneková D, Stanojevic M, Struck D, van de Vijver D, Vandamme AM, Vercauteren J
  • Publication Year: 2014
  • Journal: PLoS One
  • Link: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094495

In Europe, a continuous programme (SPREAD) has been in place for ten years to study transmission of drug resistant HIV. We analysed time trends of transmitted drug resistance mutations (TDRM) in relation to the risk behaviour reported.
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Global Dispersal Pattern of HIV Type 1 Subtype CRF01_AE: A Genetic Trace of Human Mobility Related to Heterosexual Sexual Activities Centralized in Southeast Asia

  • Authors: Albert J, Alexiev I, Angelis K, Åsjö B, Balotta C, Boucher CA, Camacho RJ, Coughlan S, Griskevicius A, Grossman Z, Hamouda O, Hatzakis A, Horban A, Kaplan L, Kostrikis LG, Lepej S, Liitsola K, Linka M, Magiorkinis G, Mamais I, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Staneková D, Stanojevic M, Struck D, Vandamme AM, Vercauteren J
  • Publication Year: 2014
  • Journal: Journal of Infectious Diseases
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/25512631

Human immunodeficiency virus type 1 (HIV-1) subtype CRF01_AE originated in Africa and then passed to Thailand, where it established a major epidemic. Despite the global presence of CRF01_AE, little is known about its subsequent dispersal pattern.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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