Biological and molecular characterization of trypanosoma cruzi strains from four states of Brazil
- Autores: Ribeiro AR, Lima L, De Almeida LA, Monteiro J, Moreno CJG, Nascimento JD, De Araújo RF, Mello F, Martins LPA, Graminha MAS, Teixeira MMG, Silva MS, Steindel M, Da Rosa JA
- Ano de Publicação: 2018
- Journal: American Journal of Tropical Medicine and Hygiene
- Link: http://www.ajtmh.org/content/journals/10.4269/ajtmh.16-0200
Chagas disease affects between six and seven million people. Its etiological agent, Trypanosoma cruzi, is classified into six discrete typing units (DTUs). The biological study of 11 T. cruzi strains presented here included four parameters: growth kinetics, parasitemia curves, rate of macrophage infection, and serology to evaluate IgM, total IgG, IgG1, IgG2a, and IgG3. Sequencing […]
Ler mais