Pneumocystis jirovecii multilocus genotyping in pooled DNA samples: a new approach for clinical and epidemiological studies.
- Autores: Antunes F, Esteves F, Gaspar J, Mansinho K, Matos O
- Journal: Clinical Microbiology and Infection
- Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Pneumocystis+jirovecii+multilocus+genotyping+in+pooled+DNA+samples%3A+a+new+approach+for+clinical+and+epidemiological+studies.
Specific single-nucleotide polymorphisms (SNPs) are recognized as important DNA sequence variations influencing the pathogenesis of Pneumocystis jirovecii and the clinical outcome of Pneumocystis pneumonia, which is a major worldwide cause of illness among immunocompromised patients