Order and disorder in viral proteins: new insights into an old paradigm.

Authors: Alves C, Cunha C
Journal: Future Virology
Link: https://apps.webofknowledge.com/full_record.do?product=UA&search_mode=GeneralSearch&qid=4&SID=T1zdDDEYC1eBxhDSCne&page=1&doc=1

The conventional dogma stating that proteins must fold into a well-defined structure In order to display biological function is being challenged everyday as new data emerge on the relevance of disordered regions and intrinsically disordered proteins. Viral proteins in particular can benefit greatly from the conformational flexibility granted by partially folded or unfolded protein segments.
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Mutations selected in HIV-2-infected patients failing a regimen including atazanavir

Authors: Aleixo MJ, Camacho RJ, Cavaco-Silva J, Cunha C, Faria D, Gomes P, Goncalves MF, Valadas E, Van Laethem K, Vandamme AM
Journal: Journal of Antimicrobial Chemotherapy
Link: http://www.ncbi.nlm.nih.gov/pubmed/22977160

To investigate mutations selected in viruses from HIV-2-infected patients failing a highly active antiretroviral treatment (HAART) regimen including atazanavir/ritonavir.
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Development of mathematical models for the analysis of hepatitis delta virus viral dynamics

Authors: Cunha C, de Sousa BC
Journal: PLoS One
Link: http://www.ncbi.nlm.nih.gov/pubmed/20862328

BACKGROUND:
Mathematical models have shown to be extremely helpful in understanding the dynamics of different virus diseases, including hepatitis B. Hepatitis D virus (HDV) is a satellite virus of the hepatitis B virus (HBV).
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Virus and non-coding RNAs: stars in the host-virus interaction game

Authors: Cunha C, Quina AS, Tavanez J
Publication Year: 2014
Journal: Future Virology
Link: http://www.futuremedicine.com/doi/abs/10.2217/fvl.14.84?journalCode=fvl

In the past few years, noncoding RNAs (ncRNAs) have emerged as key modulators of the transcriptional and post-transcriptional control of a variety of cellular processes such as development, signaling, homeostasis and oncogenesis. Like their host cells, many viruses produce ncRNAs.
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Detection of Wolbachia in Dirofilaria infected dogs in Portugal

Authors: Alho AM, Belo S, Calado M, Carvalho LM, Cunha C, Ferreira CC, Landum M, Maurício I, Meireles JS
Publication Year: 2014
Journal: Veterinary Parasitology
Link: http://www.sciencedirect.com/science/article/pii/S0304401714003069

Wolbachia pipiens, an intracellular endosymbiont bacteria of filarial nematodes, has been implicated in the pathogenesis of filarial diseases, in particular in heavy Dirofilaria spp. infections. Antibiotic therapy (doxycycline) against Wolbachia has been proven to be suitable adjunct therapy, prior to adulticide treatment of canine dirofilariosis.
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Order and disorder in viral proteins: new insights into an old paradigm.

Mutations selected in HIV-2-infected patients failing a regimen including atazanavir

Development of mathematical models for the analysis of hepatitis delta virus viral dynamics

Virus and non-coding RNAs: stars in the host-virus interaction game

Detection of Wolbachia in Dirofilaria infected dogs in Portugal

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