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Home / Archives for Afonso MO

Seasonal Dynamics of Phlebotomine Sand Fly Species Proven Vectors of Mediterranean Leishmaniasis Caused by Leishmania infantum

  • Authors: Afonso MO, Alten B, Antoniou M, Arserim SK, Bañuls AL, Bianchi R, Bongiorno G, Campino L, Cassan C, Christodoulou V, Dokianakis E, Erisoz Kasap O, Giorgobiani E, González E3, Gradoni L, Gramiccia M, Gunay F, Jimenez M, Karakus M, Kaynas S, Khoury C, Maia C, Mazeris A, Molina R, Oguz G, Ozbel Y, Prudhomme J, Rahola N, Sereno D, Thierry M, Toty C, Tsertsvadze N, Tsirigotakis N, Tskhvaradze L, Vergnes B, Volf P
  • Publication Year: 2016
  • Journal: Plos Neglected Tropical Diseases
  • Link: http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0004458

The recent geographical expansion of phlebotomine vectors of Leishmania infantum in the Mediterranean subregion has been attributed to ongoing climate changes. At these latitudes, the activity of sand flies is typically seasonal; because seasonal phenomena are also sensitive to general variations in climate, current phenological data sets can provide a baseline for continuing investigations on […]
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First molecular detection of Leishmania tarentolae-like DNA in Sergentomyia minuta in Spain

  • Authors: Afonso MO, Blanco-Ciudad J, Bravo-Barriga D, Campino L, Frontera E, Maia C, Parreira R, Pérez-Martín JE, Reina D, Serrano-Aguilera FJ
  • Publication Year: 2016
  • Journal: Parasitology Research
  • Link: https://link.springer.com/article/10.1007/s00436-015-4887-z

Phlebotomine sand flies (Diptera, Psychodidae) are vectors of multiple Leishmania species, among which Leishmania infantum stands out as a being frequently pathogenic to humans and dogs in Mediterranean countries. In this study, Sergentomyia minuta sand flies were collected using CDC miniature light traps in different 431 biotopes from Southwest Spain. A total of 114 females were tested for the presence of Leishmania DNA […]
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Detection of Leishmania DNA and blood meal sources in phlebotomine sand flies (Diptera: Psychodidae) in western of Spain: Update on distribution and risk factors associated

  • Authors: Afonso MO, Blanco-Ciudad J, Bravo-Barriga D, Campino L, Frontera E, Gómez-Gordo L, Maia C, Parreira R, Pérez-Martín JE, Reina D, Serrano FJ
  • Publication Year: 2016
  • Journal: Acta Tropica
  • Link: https://www.sciencedirect.com/science/article/pii/S0001706X16304077?via%3Dihub%20

Leishmaniosis caused by Leishmania infantum is present in Mediterranean countries, with high prevalence in areas of the center and south of Spain. However, in some regions such as Extremadura (in southwest of Spain), data has not been updated since 1997. The aim of this work was (i) to provide information about the distribution of phlebotomine […]
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Genetic structure of Phlebotomus (Larroussius) ariasi populations, the vector of Leishmania infantum in the western Mediterranean: epidemiological implications

  • Authors: Afonso MO, Alves-Pires C, Barón SD, Bounamous A, Depaquit J, Díaz V, Franco FA, Gállego M, Gálvez R, Guernaoui S, Martín-Sánchez J, Molina R, Morales-Yuste M, Morillas-Márquez F, Pesson B
  • Journal: International Journal for Parasitology
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Genetic+structure+of+Phlebotomus+(Larroussius)+ariasi+populations%2C+the+vector+of+Leishmania+infantum+in+the+western+Mediterranean%3A+Epidemiological+implications

In recent years there has been growing interest in analyzing the geographical variations between populations of different Phlebotomus spp. by comparing the sequences of various genes. However, little is known about the genetic structure of Phlebotomus ariasi. In this study, we were able to sequence a fragment of the mitochondrial Cyt b gene in 133 […]
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Leishmania infection and host-blood feeding preferences of phlebotomine sandflies and canine leishmaniasis in an endemic European area, the Algarve Region in Portugal

  • Authors: Afonso MO, Campino L, Cristóvão JM, Dionísio L, Maia C, Neto L
  • Journal: Memórias do Instituto Oswaldo Cruz
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/23827997

The Algarve Region (AR) in southern Portugal, which is an international tourist destination, has been considered an endemic region of zoonotic leishmaniasis caused by Leishmania infantum since the 1980s. In the present study, phlebotomine and canine surveys were conducted to identify sandfly blood meal sources and to update the occurrence of Leishmania infection in vectors and dogs.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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