GHTM

Global Health and Tropical Medicine

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Home / Archives for 2015

Re-Thinking Pharmaceutical Production in Africa; Insights from the Analysis of the Local Manufacturing Dynamics in Mozambique and Zimbabwe

  • Authors: Banda G, Russo G
  • Publication Year: 2015
  • Journal: Studies in Comparative International Development
  • Link: http://link.springer.com/article/10.1007%2Fs12116-015-9186-2

Until recently, consensus existed in certain circles that the African industry was not suitable for cost-effective production of quality, safe drugs. Yet, public and private pharmaceutical enterprises have cropped up on the continent, with some venturing into production of sophisticated and complex drugs, such as antiretrovirals (ARVs). In our study, we analyse and contrast the […]
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Exposure to Leishmania spp. and sand flies in domestic animals in northwestern Ethiopia

  • Authors: Baneth G, Hailu A, Jaffe CL, Kassahun A, King R, Kostalova T, Lestinova T, Maia C, Polanska N, Rohousova I, Talmi-Frank D, Volf P, Votypka J, Warburg A, Yasur-Landau D
  • Publication Year: 2015
  • Journal: Parasites & Vectors
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/26152578

BACKGROUND: Human visceral leishmaniasis caused by Leishmania donovani is considered an anthroponosis; however, Leishmania-infected animals have been increasingly reported in L. donovani foci, and the role of these animals as reservoirs for human L. donovani infection remains unclear. METHODS: We conducted a study of domestic animals (goats, sheep, cows, dogs, and donkeys) in three L. […]
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Measuring efflux and permeability in mycobacteria

  • Authors: Ainsa JA, Rodrigues L, Viveiros M
  • Publication Year: 2015
  • Journal: Mycobacteria Protocols, pp 227-239, part of the book series, Methods in Molecular Biology, 1285
  • Link: https://link.springer.com/protocol/10.1007/978-1-4939-2450-9_13

http://www.ncbi.nlm.nih.gov/pubmed/25779319
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Larvicidal Activity Against Aedes aegypti of Foeniculum vulgare Essential Oils from Portugal and Cape Verde

  • Authors: Delgado M, Figueiredo AC, Matos O, Moiteiro C, Novo MT, Rocha DK
  • Publication Year: 2015
  • Journal: Natural Product Communications
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/25973508

Dengue is a potentially fatal mosquito-borne infection with 50 million cases per year and 2.5 billion people vulnerable to the disease. This major public health problem has recurrent epidemics in Latin America and occurred recently in Cape Verde and Madeira Island. The lack of anti-viral treatment or vaccine makes the control of mosquito vectors a high option to prevent virus transmission.
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Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis

  • Authors: Aghokeng AF, Albert J, Avi R, Avila-Rios S, Bertagnolio S, Bessong PO, Blanco JL, Boucher CA, Brooks JI, Brumme ZL, Busch MP, Bussmann H, Chaix ML, Chin BS, D'Aquin TT, De Gascun CF, de Wit TR, Derache A, Descamps D, Deshpande AK, Djoko CF, Eshleman SH, Fleury H, Frange P, Fujisaki S, Hamers RL, Harrigan PR, Hattori J, Holguin A, Hunt GM, Ichimura H, Ioannidis JPA, Jordan MR, Kaleebu P, Katzenstein D, Kiertiburanakul S, Kim JH, Kim SS, Lemey P, Li Y, Lutsar I, Morris L, Ndembi N, Ng KP, Paranjape RS, Peeters M, Poljak M, Price MA, Ragonnet-Cronin ML, Reyes-Terán G, Rhee SY, Rolland M, Shafer RW, Sirivichayakul S, Smith DM, Soares MA, Soriano VV, Ssemwanga D, Stanojevic M, Stefani MA, Sugiura W, Sungkanuparph S, Tanuri A, Taylor J, Tee KK, Truong HM, Van de Vijver DA, Vandamme AM, Varghese V, Vidal N, Yang C, Yang R, Yebra G
  • Publication Year: 2015
  • Journal: Plos Medicine
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/25849352

BACKGROUND: Regional and subtype-specific mutational patterns of HIV-1 transmitted drug resistance (TDR) are essential for informing first-line antiretroviral (ARV) therapy guidelines and designing diagnostic assays for use in regions where standard genotypic resistance testing is not affordable. We sought to understand the molecular epidemiology of TDR and to identify the HIV-1 drug-resistance mutations responsible for […]
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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