GHTM

Global Health and Tropical Medicine

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Home / Archives for 2013

HIV-1 sub- type distribution and its demographic determinants in newly diagnosed patients in Europe suggest highly compartmentalized epidemics

  • Authors: Abecasis AB, Albert J, Åsjö B, Balotta C, Beshkov D, Boucher CA, Camacho RJ, Clotet B, De Gascun C, Griskevicius A, Grossman Z, Hamouda O, Horban A, Kolupajeva T, Korn K, Kostrikis LG, Kücherer C, Liitsola K, Linka M, Nielsen C, Otelea D, Paraskevis D, Paredes R, Poljak M, Puchhammer-Stöckl E, Schmit JC, Sönnerborg A, Staneková D, Stanojevic M, Struck D, Theys K, Van de Vijver DMC, Vandamme AM, Vercauteren J, Wensing AMJ
  • Publication Year: 2013
  • Journal: Retrovirology
  • Link: http://www.retrovirology.com/content/10/1/7

Understanding HIV-1 subtype distribution and epidemiology can assist preventive measures and clinical decisions. Sequence variation may affect antiviral drug resistance development, disease progression, evolutionary rates and transmission routes.
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A genomic signature and the identification of new sporulation genes

  • Authors: Abecasis AB, Alves R, Henriques AO, Pereira-Leal JB, Quintais L, Serrano M
  • Publication Year: 2013
  • Journal: Journal of Bacteriology
  • Link: http://jb.asm.org/content/195/9/2101.full

Bacterial endospores are the most resistant cell type known to humans, as they are able to withstand extremes of temperature, pressure, chemical injury, and time. They are also of interest because the endospore is the infective particle in a variety of human and livestock diseases.
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Monoclonal antibody technology applied to the detection of Cryptosporidium parvum oocysts in human and cattle fecal samples

  • Authors: Codices V, Matos O, Novo C
  • Publication Year: 2013
  • Journal: Advances in Bioscience and Biotechnology
  • Link: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=30580

With the discovery that the coccidian parasiteCryptosporidium sp. can cause severe symptoms in humans, many diagnostic techniques were quickly implemented such as microscopic visualization, immunofluorescence and PCR. Currently, there is no effective drug treatment and none of the current diagnostic methods is 100% accurate. In this study, a BALB/C mouse was subcutaneously immunized with Cryptosporidium parvum oocysts extract.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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