One-pot synthesis of dual-stimuli responsive hybrid PNIPAAm-chitosan microgels

Authors: Borges JP, Echeverria C, Ferreira I, Novo CMM, Pereira L, Robalo A, Soares P
Publication Year: 2015
Journal: Materials and Design
Link: http://www.sciencedirect.com/science/article/pii/S0264127515302392

The incorporation of magnetic nanoparticles into poly(N-isopropylacrylamide) (PNIPAAm) and chitosan microgels gives rise to hybrid systems that combine the microgels swelling capacity with the interesting features presented in magnetic nanoparticles. The presence of chitosan that act as surfactant for magnetic nanoparticles provides a simplistic approach which allows the encapsulation of magnetic nanoparticles without any previous […]
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Challenges in Antibody Development against Tn and Sialyl-Tn Antigens

Authors: Barbas A, Carrascal MA, Delannoy P, Loureiro LR, Novo C, Ramalho JS, Videira PA
Publication Year: 2015
Journal: Biomolecules
Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598775/%20

The carbohydrate antigens Tn and sialyl-Tn (STn) are expressed in most carcinomas and usually absent in healthy tissues. These antigens have been correlated with cancer progression and poor prognosis, and associated with immunosuppressive microenvironment. Presently they are used in clinical trials as therapeutic vaccination, but with limited success due to their low immunogenicity. Alternatively, anti-Tn […]
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Thermal and magnetic properties of iron oxide colloids: influence of surfactants

Authors: Borges JP, Coutinho JT, Echeverria C, Ferreira I, Lochte F, Novo C, Pereira L, Soares P
Publication Year: 2015
Journal: Nanotechnology
Link: http://iopscience.iop.org/article/10.1088/0957-4484/26/42/425704/meta

Iron oxide nanoparticles (NPs) have been extensively studied in the last few decades for several biomedical applications such as magnetic resonance imaging, magnetic drug delivery and hyperthermia. Hyperthermia is a technique used for cancer treatment which consists in inducing a temperature of about 41-45 °C in cancerous cells through magnetic NPs and an external magnetic […]
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Tuberculosis and social inequity in health: an ecological study using multivariate statistical techniques, São Paulo, Brazil

Authors: Arcêncio RA, Freitas IM, Fronteira I, Popolin MP, Rodrigues LB, Santos Neto M, Uchoa SA, Yamamura M
Publication Year: 2014
Journal: Revista Panamericana de Salud Publica
Link: http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S1020-49892014000400006

Objective: To identify the patterns of São Paulo state municipalities, in Brazil, regarding the relationship between tuberculosis and indicators of health care services, health care service availability, context, and social inequality.
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The genealogical population dynamics of HIV-1 in a large transmission chain: bridging within and among host evolutionary rates

Authors: Baele G, Derdelinckx I, Drummond A, Lemey P, Rambaut A, Suchard MA, Van Laethem K, Van Wijngaerden E, Vandamme AM, Vrancken B
Publication Year: 2014
Journal: PLoS Computational Biology
Link: http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003505

Transmission lies at the interface of human immunodeficiency virus type 1 (HIV-1) evolution within and among hosts and separates distinct selective pressures that impose differences in both the mode of diversification and the tempo of evolution. In the absence of comprehensive direct comparative analyses of the evolutionary processes at different biological scales, our understanding of how fast within-host HIV-1 evolutionary rates translate to lower rates at the between host level remains incomplete.
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One-pot synthesis of dual-stimuli responsive hybrid PNIPAAm-chitosan microgels

Challenges in Antibody Development against Tn and Sialyl-Tn Antigens

Thermal and magnetic properties of iron oxide colloids: influence of surfactants

Tuberculosis and social inequity in health: an ecological study using multivariate statistical techniques, São Paulo, Brazil

The genealogical population dynamics of HIV-1 in a large transmission chain: bridging within and among host evolutionary rates

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