Global Health and Tropical Medicine
The main focus of this study is to illustrate the importance of the statistical analysis in the evaluation of the accuracy of malaria diagnostic tests, without admitting a reference test, exploring a dataset (n=3317) collected in São Tomé and Príncipe.
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The classical latent class model assumes the hypothesis of conditional independence. We explore tools commonly used to validate this hypothesis (correlation residual plot, log-odds ratio check plot, and known goodness of fit tests) to make practitioners aware of these tools’ shortcomings in correctly identifying local dependence.
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This work overviews some developments on the estimation of the Receiver Operating Characteristic (ROC) curve. Estimation methods in this area are constantly being developed, adjusted and extended, and it is thus impossible to cover all topics and areas of application in a single paper.
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