GHTM

Global Health and Tropical Medicine

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Home / Archives for Simoes A

Contribution of efflux to colistin heteroresistance in a multidrug resistant acinetobacter baumannii clinical isolate

  • Authors: Machado D, Antunes J, Simoes A, Perdigão J, Couto I, McCusker M, Martins M, Portugal I, Pacheco T, Batista J, Toscano C, Viveiros M
  • Publication Year: 2018
  • Journal: Journal of Medical Microbiology
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/29717972

PURPOSE: The mechanisms underlying colistin heteroresistance in Acinetobacter baumannii are not fully understood. Here, we investigated the role of efflux in colistin-heteroresistant populations of a multidrug-resistant (MDR) A. baumannii clinical isolate. METHODOLOGY: Three colistin-resistant A. baumannii strain variants isolated from the same clinical sample were studied for the presence of heteroresistance to colistin by drug […]
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Implementing an antibiotic stewardship information system to improve hospital infection control: A Co-design process

  • Authors: Maia MR, Simoes A, Lapão LV
  • Publication Year: 2018
  • Journal: Studies in Health Technology and Informatics
  • Link: https://www.ncbi.nlm.nih.gov/pubmed/29677922

Abstract HAITooL information system design and implementation was based on Design Science Research Methodology, ensuring full participation, in close collaboration, of researchers and a multidisciplinary team of healthcare professionals. HAITooL enables effective monitoring of antibiotic resistance, antibiotic use and provides an antibiotic prescription decision-supporting system by clinicians, strengthening the patient safety procedures. The design, development […]
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HAITool: supporting clinical pharmacist’s role on antibiotic stewardship through an innovative information system

  • Authors: Gregório J, Lapão LV, Maia M, Simoes A
  • Publication Year: 2017
  • Journal: International Journal of Clinical Pharmacy
  • Link: http://www.pcne.org/script25.php?abstractid=154

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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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