In Silico Chemogenomics Drug Repositioning Strategies for Neglected Tropical Diseases
- Authors: Andrade CH, Neves BJ, Melo-Filho CC, Rodrigues J, Silva DC, Braga RC, Cravo P
- Publication Year: 2019
- Journal: Current Medicinal Chemistry
- Link: https://www.ncbi.nlm.nih.gov/pubmed/29521204
Only ~1% of all drug candidates against Neglected Tropical Diseases (NTDs) have reached clinical trials in the last decades, underscoring the need for new, safe and effective treatments. In such context, drug repositioning, which allows finding novel indications for approved drugs whose pharmacokinetic and safety profiles are already known, emerging as a promising strategy for […]
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