The role of the immunological background of mice in the genetic variability of Schistosoma mansoni as detected by random amplification of polymorphic DNA

• Autores: Afonso A, Belo S, Calado M, Cossa-Moiane IL, Ferreira PM, Maurício I, Mendes T
• Ano de Publicação: 2014
• Journal: Journal of Helminthology
• Link: http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=9992333

Schistosomiasis is a parasitic disease caused by flatworms of the genus Schistosoma. Among the Schistosomaspecies known to infect humans, S. mansoni is the most frequent cause of intestinal schistosomiasis in sub-Saharan Africa and South America: the World Health Organization estimates that about 200,000 deaths per year result from schistosomiasis in sub-Saharan Africa alone. The Schistosoma life cycle requires two different hosts: a snail as intermediate host and a mammal as definitive host.
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