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Home / Archives for Coelho TS

Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis

  • Autores: Coelho TS, Couto I, Machado D, Maschmann RA, Perdigão J, Pereira C, Portugal I, Ramos DF, Rossetti MLR, Silva PA, Viveiros M, von Groll A
  • Ano de Publicação: 2017
  • Journal: Frontiers in Microbiology
  • Link: https://www.frontiersin.org/articles/10.3389/fmicb.2017.00711/full

Numerous studies show efflux as a universal bacterial mechanism contributing to antibiotic resistance and also that the activity of the antibiotics subject to efflux can be enhanced by the combined use of efflux inhibitors. Nevertheless, the contribution of efflux to the overall drug resistance levels of clinical isolates of Mycobacterium tuberculosis is poorly understood and […]
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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+351 213 652 600
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