The first detection of Leishmania major in naturally infected Sergentomyia minuta in Portugal

Authors: Afonso MO, Campino L, Cortes S, Dionísio L, Maia C, Neto L
Publication Year: 2013
Journal: Memórias do Instituto Oswaldo Cruz
Link: http://www.ncbi.nlm.nih.gov/pubmed/23828004

Phlebotomine sandflies of the genus Sergentomyia are widely distributed throughout the Old World. It has been suggested that Sergentomyia spp are involved in the transmission of Leishmania in India and Africa, whereas Phlebotomus spp are thought to be the sole vectors of Leishmania in the Old World. In this study, Leishmania major DNA was detected in one Sergentomyia minuta specimen that was collected in the southern region of Portugal. This study challenges the dogma that Leishmania is exclusively transmitted by species of the genus Phlebotomus in the Old World.
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Entomological and ecological studies in a new potential zoonotic leishmaniasis focus in Torres Novas municipality, Central Region, Portugal

Authors: Afonso MO, Alves-Pires C, Branco S, Campino L, Cortes S, Cristóvão JM, Gonçalves L, Maia C
Publication Year: 2013
Journal: Acta Tropica
Link: http://www.ncbi.nlm.nih.gov/pubmed/23262215

In Portugal human and canine leishmaniasis are caused by Leishmania infantum, and Phlebotomus perniciosus and P. ariasi are the proven vectors. Three main foci were identified in eighty’s decade: Trás-os-Montes and Alto Douro region, Lisbon region and Algarve region, but according to OnLeish observatory data, canine leishmaniasis cases have been reported from several other regions, for which sand fly species and their infection rates are unknown.
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Molecular Identification of Borrelia miyamotoi in Ixodes ricinus from Portugal

Authors: Campino L, Carreira T, Faria S, Lopes N, Maia C, Nunes M, Parreira R, Sousa C, Vieira ML
Publication Year: 2015
Journal: Vector-Borne and Zoonotic Diseases
Link: http://www.ncbi.nlm.nih.gov/pubmed/26273814

Borrelia miyamotoi, a relapsing fever spirochete, has been found recently in Ixodes ricinus ticks; however, little is known about its spatial distribution and potential local impact on human health. A total of 640 ticks (447 nymphs and 193 adults) collected throughout Portugal were analyzed using two nested PCR protocols, one targeting the flagellin gene and […]
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Molecular detection of Leishmania DNA and identification of blood meals in wild caught phlebotomine sand flies (Diptera: Psychodidae) from southern Portugal

Authors: Afonso MO, Campino L, Cristóvão JM, Freitas FB, Maia C, Parreira R
Publication Year: 2015
Journal: Parasites & Vectors
Link: http://www.ncbi.nlm.nih.gov/pubmed/25889732

Authors: Albuquerque A, Cabral LIL, Campino L, Cortes S, Cristiano MLS, Lopes L
Publication Year: 2015
Journal: Antimicrobial Agents and Chemotherapy
Link: http://aac.asm.org/content/59/8/5032.full

Leishmaniasis is among the world’s most neglected diseases. Currently available drugs for treatment present drawbacks, urging the need for more effective, safer, and cheaper drugs. A small library of artemisinin-derived trioxanes and synthetic trioxolanes was tested against promastigote and intramacrophage amastigote forms of Leishmania infantum. The trioxolanes LC50 and LC95 presented the best activity and […]
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The first detection of Leishmania major in naturally infected Sergentomyia minuta in Portugal

Entomological and ecological studies in a new potential zoonotic leishmaniasis focus in Torres Novas municipality, Central Region, Portugal

Molecular Identification of Borrelia miyamotoi in Ixodes ricinus from Portugal

Molecular detection of Leishmania DNA and identification of blood meals in wild caught phlebotomine sand flies (Diptera: Psychodidae) from southern Portugal

In Vitro Susceptibility of Leishmania infantum to Artemisinin Derivatives and Selected Trioxolanes

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