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Global Health and Tropical Medicine

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Home / Archives for Lopes L

Kaposi’s sarcoma presenting as violaceous macules on the chest of a kidney transplanted patient

  • Autores: Borges-Costa J, Guerra J, Lopes L, Soares-Almeida L
  • Ano de Publicação: 2016
  • Journal: BMJ Case Reports
  • Link: http://casereports.bmj.com/content/2016/bcr-2015-210999

Organ transplant recipients have a high incidence of cancer associated with persistent viral infections, such as human herpes virus 8. This virus is associated with Kaposi’s sarcoma, and a change in the dose or type of immunosuppression regimen should be the first step in its treatment. A multidisciplinary approach with nephrologists, dermatologists and oncologists is […]
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Syphilis: Prevalence in a Lisbon hospital

  • Autores: Borges-Costa J, Ferro-Rodrigues R, Lito L, Llobet S, Lopes L
  • Ano de Publicação: 2016
  • Journal: Acta Médica Portuguesa

INTRODUCTION: Syphilis is a sexual and vertical transmitted disease. Its incidence is increasing in Europe, particularly, in Portugal. MATERIAL AND METHODS: A descriptive, retrospective study was performed based on positive treponemal tests from January to December 2013, at the Santa Maria Hospital, Lisbon. In-patients and out-patients evaluated in medical appointments and at the emergency department […]
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An atypical case of cutaneous leishmaniasis caused by Leishmania infantum in Portugal

  • Autores: Borges-Costa J, Campino L, Filipe P, Lopes L, Soares-Almeida L, Vasconcelos P
  • Journal: Dermatology Online Journal
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/24314782

Leishmaniasis is a parasitic disease caused by an intracellular protozoan that belongs to the genus Leishmania and is transmitted by a phlebotomine sandfly. In Southwest Europe, including Portugal, cutaneous leishmaniasis is considered a rare disease of unknown or underestimated prevalence. Leishmania infantum is the only species identified as responsible for the autochthonous cases.
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In Vitro Susceptibility of Leishmania infantum to Artemisinin Derivatives and Selected Trioxolanes

  • Autores: Albuquerque A, Cabral LIL, Campino L, Cortes S, Cristiano MLS, Lopes L
  • Ano de Publicação: 2015
  • Journal: Antimicrobial Agents and Chemotherapy
  • Link: http://aac.asm.org/content/59/8/5032.full

Leishmaniasis is among the world’s most neglected diseases. Currently available drugs for treatment present drawbacks, urging the need for more effective, safer, and cheaper drugs. A small library of artemisinin-derived trioxanes and synthetic trioxolanes was tested against promastigote and intramacrophage amastigote forms of Leishmania infantum. The trioxolanes LC50 and LC95 presented the best activity and […]
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About GHTM

GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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