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Home / Archives for Borges L

Publications

Gene expression changes in the salivary glands of Anopheles coluzzii elicited by Plasmodium berghei infection

  • Authors: Borges L, Cabezas-Cruz A, Coelho LP, de la Fuente J, Do Rosário V, Domingos A, Pinheiro-Silva R, Valdés JJ
  • Publication Year: 2015
  • Journal: Parasites & Vectors
  • Link: https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-015-1079-8%20

Malaria is a devastating infectious disease caused by Plasmodium parasites transmitted through the bites of infected Anopheles mosquitoes. Salivary glands are the only mosquito tissue invaded by Plasmodium sporozoites, being a key stage for the effective parasite transmission, making the study of Anopheles sialome highly relevant. RNA-sequencing was used to compare differential gene expression in […]
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Trypanosoma cruzi IV causing outbreaks of acute Chagas disease and infections by different haplotypes in the Western Brazilian Amazonia

  • Authors: Barbosa Md, Borges L, de Sá AR, Gomes ML, Guerra JA, Magalhaes LK, Monteiro WM, Pires I, Silveira H, Toledo MJ
  • Journal: PLoS One
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Trypanosoma+cruzi+IV+Causing+Outbreaks+of+Acute+Chagas+Disease+and+Infections+by+Different+Haplotypes+in+the+Western+Brazilian+Amazonia.

Chagas disease is an emergent tropical disease in the Brazilian Amazon Region, with an increasing number of cases in recent decades. In this region, the sylvatic cycle of Trypanosoma cruzi transmission, which constitutes a reservoir of parasites that might be associated with specific molecular, epidemiological and clinical traits, has been little explored.
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Approaches towards tick and tick-borne diseases control

  • Authors: Antunes S, Borges L, Do Rosário VE, Domingos A
  • Publication Year: 2013
  • Journal: Revista da Sociedade Brasileira de Medicina Tropical
  • Link: http://www.scielo.br/scielo.php?pid=S0037-86822013000300265&script=sci_arttext

Ticks are obligate haematophagous ectoparasites of wild and domestic animals as well as humans, considered to be second worldwide to mosquitoes as vectors of human diseases. Tick-borne diseases are responsible worldwide for great economic losses in terms of mortality and morbidity of livestock animals. This review concerns to the different tick and tick-parasites control methods having a major focus on vaccines.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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