Antimicrobial and Efflux Inhibitor Activity of Usnic Acid Against Mycobacterium abscessus

• Authors: Ramis IB, Vianna JS, Reis AJ, von Groll A, Ramos DF, Viveiros M, da Silva PEA
• Publication Year: 2018
• Journal: Planta Medica
• Link: https://www.ncbi.nlm.nih.gov/pubmed/29913527

New drugs are needed to treat infections with antimicrobial-resistant Mycobacterium abscessus; therefore, we evaluated usnic acid as an antimicrobial agent and efflux inhibitor (EI) against M. abscessus. Usnic acid showed antimicrobial activity, and synergistically, the EI verapamil increased this activity. In addition, when we evaluated the interaction of antimicrobials with usnic acid, the increase of their activity was […]
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