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Home / Archives for Malaria Journal

Evaluation of prevalence’s of pfdhfr and pfdhps mutations in Angola.

  • Authors: Dimbu R, Do Rosário VE, Figueiredo P, Fortes F, Lopes D, Neto Z
  • Journal: Malaria Journal
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Evaluation+of+prevalence%27s+of+pfdhfr+and+pfdhps+mutations+in+Angola.

BACKGROUND:
Malaria is the major cause of morbidity and mortality in Angola. The most vulnerable groups to Plasmodium falciparum infection are pregnant women and children under five years of age.
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Potential threat of malaria epidemics in a low transmission area, as exemplified by São Tomé and Príncipe

  • Authors: Do Rosário VE, Lee PW, Liu CT, Rampao HS, Shaio MF
  • Journal: Malaria Journal
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/?term=Potential+threat+of+malaria+epidemics+in+a+low+transmission+area%2C+as+exemplified+by+S%C3%A3o+Tom%C3%A9+and+Pr%C3%ADncipe

BACKGROUND: Plasmodium falciparum is the major cause of malaria infection in the island of São Tomé, in the Republic of São Tomé and Príncipe (STP), with an incidence of 40 – 50% before 2004. Since 2004, through the coordination of the Ministry of Health of STP and their Centro Nacional de Endemias (CNE), an integrated […]
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Impact of a training course on the quality of malaria diagnosis by microscopy in Angola

  • Authors: Bernardino L, Brito M, Fançony C, Fortes F, Mirante C, Moura S, Neves M, Sambo MR
  • Publication Year: 2014
  • Journal: Malaria Journal
  • Link: http://www.malariajournal.com/content/13/1/437

This study was implemented in laboratories from three hospitals in different provinces of Angola: Bengo, Benguela and Luanda. In each laboratory samples were collected before and after the training course (slide with thin and thick blood smears, a dried blood spot and a form).
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Prevalence of pfmdr1 alleles associated with artemether-lumefantrine tolerance/resistance in Maputo before and after the implementation of artemisinin-based combination therapy

  • Authors: de Sousa B, Fernandes N, Figueiredo P, Lobo E, Lobo L, Nogueira F, Pateira S, Rosa S
  • Publication Year: 2014
  • Journal: Malaria Journal
  • Link: http://www.malariajournal.com/content/13/1/300

Mozambique implemented artemisinin-based combinations therapy (ACT) using artemether-lumefantrine (AL) as the first-line treatment for uncomplicated malaria in 2009. AL remains highly efficacious, but widespread use may soon facilitate emergence of artemisinin tolerance/resistance. The prevalence of pfmdr1 different alleles in Maputo and Mozambique is not known, either after or before the introduction of ACT. Pfmdr1 molecular markers related to Plasmodium falciparum susceptibility were analysed before and after transition to ACT.
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First report of an exophilic Anopheles arabiensis population in Bissau City, Guinea-Bissau: recent introduction or sampling bias?

  • Authors: Caputo B, Della Torre A, Dinis J, Gordicho V, Palsson K, Pinto J, Pombi M, Rodrigues A, Seixas G, Sousa CA, Vicente JL, Weetman D
  • Publication Year: 2014
  • Journal: Malaria Journal
  • Link: http://www.malariajournal.com/content/13/1/423

This study reports for the first time the presence of An. arabiensis in Antula, a suburb of Bissau city, the capital of Guinea Bissau, where high levels of hybridization between Anopheles coluzzii and An. gambiae have been reported. Given that previous surveys in the area, based on indoor collections, did not sample An. arabiensis, the possibility of a recently introduced exophilic population was investigated.
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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