Date: 20 November 2024
Time: 11:00-13:00
Location: ZOOM & Sala Fraga de Azevedo | IHMT-NOVA
GHTM Exploratory Projects 2022: Key Results
Starting from 2022, GHTM has financed innovative and multidisciplinary projects aimed at enhance«ing our understanding of infectious diseases and tropical medicine, thereby improving global health. This initiative has been dedicated to promote collaboration within the center, foster innovative ideas, and maximize the impact of existing data.
The projects financed under the first competitive call have now concluded and are ready to share key results with our GHTM community.
DrugsforNg – Liliana Rodrigues
This project addresses the global health threat of antimicrobial resistance (AMR) in Neisseria gonorrhoeae (Ng), a priority pathogen for which new treatments are urgently needed. Efflux pumps, key to developing drug resistance in Ng, are targeted for drug discovery. By repurposing existing approved drugs, the project aims to determine their in vitro activity against Ng. Preliminary data suggests at least 30 Ng targets interacting with over 50 approved drugs, potentially accelerating the discovery of new treatments for gonorrhea
RESMALDETECT – Márcia Medeiros
This project aimed to develop a low-cost and portable biosensor platform for the rapid detection of SNPs in the dhfr and dhps Plasmodium falciparum genes, which are associated with antifolate drug resistance in malaria. Using isothermal amplification approach of nucleotides, the project expected to create a prototype for quickly and selectively identifying drug-resistant malaria parasites.”
WasteWaterVir – Sofia Seabra
If you are not a GHTM member and would like to join the session, please contact us at ghtm-info@ihmt.unl.pt.