Novel Single Nucleotide Polymorphism-Based Assay for Genotyping Mycobacterium avium subsp Paratuberculosis
- Autores: Bryant J, Goldstone RJ, Inácio J, Leao C, McLuckie J, Smith DG, Stevenson K
- Ano de Publicação: 2016
- Journal: Journal Of Clinical Microbiology
- Link: http://jcm.asm.org/content/54/3/556.abstract?utm_source=TrendMDJClinMicrobiol&utm_medium=TrendMDJClinMicrobiol&utm_campaign=TrendMD_JCMCLIN_1
Typing of Mycobacterium avium subspecies paratuberculosis strains presents a challenge, since they are genetically monomorphic and traditional molecular techniques have limited discriminatory power. The recent advances and availability of whole-genome sequencing have extended possibilities for the characterization of Mycobacterium avium subspecies paratuberculosis, and whole-genome sequencing can provide a phylogenetic context to facilitate global epidemiology studies. In this study, we developed a single […]
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