Cross-Reactivity Using Chimeric Trypanosoma cruzi Antigens: Diagnostic performance in settings where Chagas disease and American cutaneous or visceral leishmaniasis are coendemic

Authors: Daltro RT, Leony LM, Freitas NEM, Silva ÂAO, Santos EF, Del-Rei RP, Brito MEF, Brandão-Filho SP, Gomes YM, Silva MS, Donato ST, Jeronimo SMB, Monteiro GRG, Carvalho LP, Magalhães AS, Zanchin NIT, Celedon PAF, Santos FLN
Publication Year: 2019
Journal: Journal Of Clinical Microbiology
Link: https://www.ncbi.nlm.nih.gov/pubmed/31189586

Chimeric T. cruzi antigens have been proposed as a diagnostic tool for chronic Chagas disease (CD) in both settings where Chagas disease is endemic and those where it is not endemic. Antibody response varies in accordance to each T. cruzi strain, presenting challenges to the use of antigens lacking demonstrated cross-reactivity with Leishmania spp. Our group expressed four chimeric proteins (IBMP-8.1, […]
Read More

Novel Single Nucleotide Polymorphism-Based Assay for Genotyping Mycobacterium avium subsp Paratuberculosis

Typing of Mycobacterium avium subspecies paratuberculosis strains presents a challenge, since they are genetically monomorphic and traditional molecular techniques have limited discriminatory power. The recent advances and availability of whole-genome sequencing have extended possibilities for the characterization of Mycobacterium avium subspecies paratuberculosis, and whole-genome sequencing can provide a phylogenetic context to facilitate global epidemiology studies. In this study, we developed a single […]
Read More

Cross-Reactivity Using Chimeric Trypanosoma cruzi Antigens: Diagnostic performance in settings where Chagas disease and American cutaneous or visceral leishmaniasis are coendemic

Novel Single Nucleotide Polymorphism-Based Assay for Genotyping Mycobacterium avium subsp Paratuberculosis

About GHTM

Contacts

Map