Hemozoin activates the innate immune system and reduces Plasmodium berghei infection in Anopheles gambiae

• Authors: Gonçalves L, Silveira H, Simoes ML
• Publication Year: 2015
• Journal: Parasites & Vectors
• Link: https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-014-0619-y

Malaria is a worldwide infectious disease caused by Plasmodium parasites and transmitted by female Anopheles mosquitoes. The malaria vector mosquito Anophelescan trigger effective mechanisms to control completion of the Plasmodium lifecycle; the mosquito immune response to the parasite involves several pathways which are not yet well characterized. Plasmodium metabolite hemozoin has emerged as a potent immunostimulator of mammalian tissues. In this study, we aim […]
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