Hemisynthetic trifluralin analogues incorporated in liposomes for the treatment of leishmanial infections
- Authors: Carvalheiro M, Cruz ME, Eleuterio CV, Esteves MA, Lopes RM, Rodrigues MA, Santos-Gomes G, Santos-Mateus D, Scoulica E
- Publication Year: 2015
- Journal: European Journal of Pharmaceutics and Biopharmaceutics
- Link: https://www.sciencedirect.com/science/article/pii/S0939641115001988?via%3Dihub
Leishmaniasis, a vector-borne parasitic disease caused by Leishmania protozoa, is one of the most neglected tropical diseases in terms of drug discovery and development. Current treatment is based on a limited number of chemotherapeutic agents all of which present either/or resistance issues, severe toxicities and adverse reactions associated with extended treatment regimens, and high cost […]
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