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Home / Archives for Dinache A

The in vitro activity of products formed from exposure of chlorpromazine to a 266nm laser beam against species of mycobacteria of human interest

  • Autores: Alexandru T, Amaral L, Armada AM, Boni M, Danko B, Dinache A, Hunyadi A, Machado D, Molnar J, Nastasa V, Pascu ML, Ramos J, Viveiros M
  • Ano de Publicação: 2013
  • Journal: In vivo
  • Link: http://www.ncbi.nlm.nih.gov/pubmed/23988894

Chlorpromazine (CPZ) was exposed to a 266 nm laser beam for different periods of time ranging from minutes to 24 h. At intervals, the products from irradiation were evaluated by thin-layer chromatography (TLC) and evaluated for their activity against mycobacteria of human interest (Mycobacterium tuberculosis, M. avium, M. intracellulare and their corresponding reference strains or clinical isolates).
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GHTM is a R&D Center that brings together researchers from IHMT with a track record in Tropical Medicine and International/Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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