Tetrahydropyridine derivative as efflux inhibitor in Mycobacterium abscessus
- Autores: Vianna JS, Ramis IB, Bierhals D, von Groll A, Ramos DF, Zanatta N, Lourenço MC, Viveiros M, Almeida da Silva PE
- Ano de Publicação: 2019
- Journal: Journal of General Virology
- Link: https://www.ncbi.nlm.nih.gov/pubmed/30630106
OBJECTIVES: This study aimed to evaluate a tetrahydropyridine derivative (THP) as a potential inhibitor of the efflux mechanism and modulator of the high level of antimicrobial resistance usually observed in members of the Mycobacterium abscessus (M. abscessus) group. METHODS: The strain M. abscessus subsp. abscessus (ATCC 19997) was used as reference, in addition to three […]
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