Andreia Albuquerque-Wendt

EDUCATION

26/01/2018 – Doctor of Philosophy (PhD), Molecular Medicine, Medizinische Hochschule Hannover, DE. Thesis title: Glycosylation in Apicomplexan Parasites. Supervisor: Prof. Dr. Françoise Routier

11/12/2013 – Master (MSc) of Biomedical Sciences – Molecular Biology and International Tropical Medicine, Instituto de Higiene e Medicina Tropical – Universidade Nova de Lisboa, PT. Thesis title: New species of Leishmania and hybrids – implications in the pathogenesis of infection. Supervisors: Prof. Dr. Lenea Campino and Dr. Sofia Cortes

23/09/2011 – Bachelor (BSc) in Biochemistry, Faculdade de Ciências e Tecnologias, Universidade NOVA de Lisboa, Monte da Caparica, PT. Thesis title: Spectroscopic characterization of chalcone (1E, 4E)-1,5-BIS(4-hidroxyfenyl)penta-1,4-diene-3-one. Supervisor: Prof. Dr. César Laia

15/09/2010 – Bachelor (BSc) in Applied Chemistry – Biotechnology, Faculdade de Ciências e Tecnologias, Universidade NOVA de Lisboa, Monte da Caparica, PT. Thesis title: Study of in vitro biological behavior of parental and hybrid strains of Leishmania. Supervisors: Prof. Dr. Lenea Campino and Dr. Sofia Cortes

EMPLOYMENT HISTORY

Since  01/11/2024 Advanced postdoctoral researcher (MSCA GF Fellow), Swiss TPH, Basel, Switzerland & Faculty of Sciences, Charles University, Prague, Czech Republic 

01/11/2023 – 31/10/2024 Advanced postdoctoral researcher, Institute of Cell Biology, University of Bern, Bern, Switzerland 

01/09/2020 – 30/08/2023 Postdoctoral researcher, Wellcome Centre for Integrative Parasitology, Institute of Infection & Immunity, College of Medical Veterinary & Life Sciences, University of Glasgow, Glasgow, UK 

01/09/2018 – 30/08/2020 Postdoctoral researcher (MSCA IF Fellow), Sir William Dunn School of Pathology, University of Oxford, United Kingdom 

01/02/2018 – 30/08/2018 Postdoctoral researcher, Instituts für Klinische Biochemie, Medizinische Hochschule Hannover, DE 

01/06/2011 – 30/06/2014 Research Assistant, Unidade de Parasitologia Médica, Instituto de Higiene e Medicina Tropical – Universidade NOVA de Lisboa, Lisbon, PT 

More information here.

Dr. Wendt graduated in 2018 from the Medizinische Hochschule Hannover, with a PhD in Molecular Medicine. During her first postdoc in the laboratory of Prof. Eva Gluenz, she focused on the role of the Leishmania mexicana transportome across its life cycle using BAR-seq methodologies.

Recently, she started a second postdoctoral project focusing on the development of anti-Leishmania transmission blocking sand fly sugar baits supported by Prof. Pascal Maeser and Prof. Petr Volf. Dr. Wendt’s research aims to explore the intricate details of host-pathogen-vector interactions in Leishmania infections and ultimately harvest basic information for the development of control strategies contributing for the eradication of leishmaniases.

1. A. Albuquerque-Wendt, C. McCoy, R. Neish, U. Dobramysl, Ç. Alagöz, T. Beneke, S.A. Cowley, K. Crouch, R.J. Wheeler, J.C. Mottram and E. Gluenz. TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen. Nature communications, 2025. Doi: 10.1038/s41467-024-55538-7
2. Ricce Espada, A. Albuquerque-Wendt, V. Hornillos, E. Gluenz, A.C. Coelho, S. Uliana. Ros3 (Lem3p/CDC50) gene dosage is implicated in miltefosine susceptibility in Leishmania (Viannia) braziliensis clinical isolates and in Leishmania (Leishmania) major. ACS Infectious Diseases, 2021, 7(4):849-858. doi: 10.1021/acsinfecdis.0c00857.
3. Albuquerque-Wendt, D. Jacot, N. Pacheco, C. Seegers, P. Zarnovican, D. Soldati-Favre, H. Bakker, F. H. Routier. C-Mannosylation of Toxoplasma gondii proteins promotes attachment to host cells and parasite virulence. Journal of Biological Chemistry, 2020, 295(4): 1066-1076. Doi: 10.1074/jbc.RA119.010590.
4. Albuquerque-Wendt, H. J. Hütte, F. F. R. F. Buettner, H. Routier, H. Bakker. Membrane Topological Model of Glycosyltransferases of the GT-C Superfamily. International journal of molecular sciences, 2019, 20(19): E4842. Doi: 10.3390/ijms20194842.
5. G. Bandini*, A. Albuquerque-Wendt*, J. Hegermann, J. Samuelson, F. H. Routier. Protein O- and C-glycosylation pathways in Plasmodium falciparum and Toxoplasma gondii. Parasitology, 2019, 146(14): 1755-1766. Doi: 10.1017/S0031182019000040. (*co-first).