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Andreia Albuquerque-Wendt
GHTM Group: VBD PhD members, Vector-borne diseases
EDUCATION
26/01/2018 – Doctor of Philosophy (PhD), Molecular Medicine, Medizinische Hochschule Hannover, DE. Thesis title: Glycosylation in Apicomplexan Parasites. Supervisor: Prof. Dr. Françoise Routier
11/12/2013 – Master (MSc) of Biomedical Sciences – Molecular Biology and International Tropical Medicine, Instituto de Higiene e Medicina Tropical – Universidade Nova de Lisboa, PT. Thesis title: New species of Leishmania and hybrids – implications in the pathogenesis of infection. Supervisors: Prof. Dr. Lenea Campino and Dr. Sofia Cortes
23/09/2011 – Bachelor (BSc) in Biochemistry, Faculdade de Ciências e Tecnologias, Universidade NOVA de Lisboa, Monte da Caparica, PT. Thesis title: Spectroscopic characterization of chalcone (1E, 4E)-1,5-BIS(4-hidroxyfenyl)penta-1,4-diene-3-one. Supervisor: Prof. Dr. César Laia
15/09/2010 – Bachelor (BSc) in Applied Chemistry – Biotechnology, Faculdade de Ciências e Tecnologias, Universidade NOVA de Lisboa, Monte da Caparica, PT. Thesis title: Study of in vitro biological behavior of parental and hybrid strains of Leishmania. Supervisors: Prof. Dr. Lenea Campino and Dr. Sofia Cortes
EMPLOYMENT HISTORY
Since 01/11/2024 Advanced postdoctoral researcher (MSCA GF Fellow), Swiss TPH, Basel, Switzerland & Faculty of Sciences, Charles University, Prague, Czech Republic
01/11/2023 – 31/10/2024 Advanced postdoctoral researcher, Institute of Cell Biology, University of Bern, Bern, Switzerland
01/09/2020 – 30/08/2023 Postdoctoral researcher, Wellcome Centre for Integrative Parasitology, Institute of Infection & Immunity, College of Medical Veterinary & Life Sciences, University of Glasgow, Glasgow, UK
01/09/2018 – 30/08/2020 Postdoctoral researcher (MSCA IF Fellow), Sir William Dunn School of Pathology, University of Oxford, United Kingdom
01/02/2018 – 30/08/2018 Postdoctoral researcher, Instituts für Klinische Biochemie, Medizinische Hochschule Hannover, DE
01/06/2011 – 30/06/2014 Research Assistant, Unidade de Parasitologia Médica, Instituto de Higiene e Medicina Tropical – Universidade NOVA de Lisboa, Lisbon, PT
More information here.
For the last 14 years, while working in different cities within Portugal, Germany, Switzerland and the United Kingdom, I have developed a toolkit focused on Biochemistry, Glycobiology, Gene Editing, Cell and Molecular Biology, applied to the study of host-protozoan parasite interactions, namely Toxoplasma gondii and Leishmania sp.
My research aims to explore the intricate details of host-pathogen-vector interactions in Leishmania infections and ultimately harvest basic information for the development of control strategies contributing for the eradication of leishmaniasis.
- A. Albuquerque-Wendt, C. McCoy, R. Neish, U. Dobramysl, T. Beneke, S.A. Cowley, K. Crouch, R.J. Wheeler, J.C. Mottram and E. Gluenz. TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen. bioRxiv, 2024. Doi: 10.1101/2024.06.21.600025.
- Ricce Espada, A. Albuquerque-Wendt, V. Hornillos, E. Gluenz, A.C. Coelho, S. Uliana. Ros3 (Lem3p/CDC50) gene dosage is implicated in miltefosine susceptibility in Leishmania (Viannia) braziliensis clinical isolates and in Leishmania (Leishmania) major. ACS Infectious Diseases, 2021, 7(4):849-858. doi: 10.1021/acsinfecdis.0c00857.
- Albuquerque-Wendt, D. Jacot, N. Pacheco, C. Seegers, P. Zarnovican, D. Soldati-Favre, H. Bakker, F. H. Routier. C-Mannosylation of Toxoplasma gondii proteins promotes attachment to host cells and parasite virulence. Journal of Biological Chemistry, 2020, 295(4): 1066-1076. Doi: 10.1074/jbc.RA119.010590.
- Albuquerque-Wendt, H. J. Hütte, F. F. R. F. Buettner, H. Routier, H. Bakker. Membrane Topological Model of Glycosyltransferases of the GT-C Superfamily. International journal of molecular sciences, 2019, 20(19): E4842. Doi: 10.3390/ijms20194842.
- G. Bandini*, A. Albuquerque-Wendt*, J. Hegermann, J. Samuelson, F. H. Routier. Protein O- and C-glycosylation pathways in Plasmodium falciparum and Toxoplasma gondii. Parasitology, 2019, 146(14): 1755-1766. Doi: 10.1017/S0031182019000040. (*co-first).