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Home / Archives for Sousa CA

Massive introgression drives species radiation at the range limit of Anopheles gambiae

  • Authors: Antao T, Bottà G, Caputo B, Clarkson CS, Dinis J, Donnelly MJ, Drury E, Gomes B, Kwiatkowski DP, Mancini E, Mead D, Miles A, Petrarca V, Pinto J, Pombi M, Rodrigues A, Sousa CA, Stalker J, Torre AD, Vicente JL, Weetman D
  • Publication Year: 2017
  • Journal: Scientific Reports
  • Link: https://www.nature.com/articles/srep46451

Impacts of introgressive hybridisation may range from genomic erosion and species collapse to rapid adaptation and speciation but opportunities to study these dynamics are rare. We investigated the extent, causes and consequences of a hybrid zone between Anopheles coluzzii and Anopheles gambiae in Guinea-Bissau, where high hybridisation rates appear to be stable at least since […]
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Insecticide resistance is mediated by multiple mechanisms in recently introduced Aedes aegypti from Madeira Island (Portugal)

  • Authors: Grigoraki L, Pinto J, Seixas G, Silva AC, Sousa CA, Vicente JL, Vontas J, Weetman D
  • Publication Year: 2017
  • Journal: Plos Neglected Tropical Diseases
  • Link: http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0005799

BACKGROUND: Aedes aegypti is a major mosquito vector of arboviruses, including dengue, chikungunya and Zika. In 2005, Ae. aegypti was identified for the first time in Madeira Island. Despite an initial insecticide-based vector control program, the species expanded throughout the Southern coast of the island, suggesting the presence of insecticide resistance. Here, we characterized the […]
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From the Laboratory to the Field: Updating Capacity Building in Medical Entomology

  • Authors: Almeida APG, Fouque F, Launois P, Silveira H, Sousa CA
  • Publication Year: 2017
  • Journal: Trends in Parasitology
  • Link: http://www.cell.com/trends/parasitology/fulltext/S1471-4922(17)30134-4?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS1471492217301344%3Fshowall%3Dtrue

Training and innovation in the field of medical entomology are essential to mitigate the burden of vector-borne diseases globally. However, there is a shortage of medical entomologists worldwide, and there are large discrepancies in capacity building in this field. In this article, we discuss the current situation, what is needed from the medical entomologist of […]
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Zika Virus, a New Threat for Europe?

  • Authors: Failloux AB, Jupille H, Mousson L, Seixas G, Sousa CA
  • Publication Year: 2016
  • Journal: Plos Neglected Tropical Diseases
  • Link: http://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0004901

BACKGROUND: Since its emergence in 2007 in Micronesia and Polynesia, the arthropod-borne flavivirus Zika virus (ZIKV) has spread in the Americas and the Caribbean, following first detection in Brazil in May 2015. The risk of ZIKV emergence in Europe increases as imported cases are repeatedly reported. Together with chikungunya virus (CHIKV) and dengue virus (DENV), […]
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Global genetic diversity of Aedes aegypti

  • Authors: Ayala D, Bheecarry A, Calderon-Arguedas O, Chadee DD, Chiappero M, Coetzee M, Elahee KB, Fernandez-Salas I, Gloria-Soria A, Kamal HA, Kamgang B, Khater EI, Kramer LD, Kramer V, Lopez-Solis A, Lutomiah J, Martins A, Micieli MV, Paupy C, Ponlawat A, Powell JR, Rahola N, Rasheed SB, Richardson JB, Saleh AA, Sanchez-Casas RM, Seixas G, Sousa CA, Tabachnick WJ, Troyo A
  • Publication Year: 2016
  • Journal: Molecular Ecology
  • Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123671/

Mosquitoes, especially Aedes aegypti, are becoming important models for studying invasion biology. We characterized genetic variation at 12 microsatellite loci in 79 populations of Ae. aegypti from 30 countries in six continents, and used them to infer historical and modern patterns of invasion. Our results support the two subspecies Ae. aegypti formosus and Ae. aegypti aegypti as genetically […]
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About GHTM

GHTM is a R&D Unit that brings together researchers with a track record in Tropical Medicine and International & Global Health. It aims at strengthening Portugal's role as a leading partner in the development and implementation of a global health research agenda. Our evidence-based interventions contribute to the promotion of equity in health and to improve the health of populations.

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